Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 2/20 | 0.35 |
| ▸ | NSD3 | Q9BZ95 | 2/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.31 |
| ▸ | EIF2AK3 | Q9NZJ5 | 2/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
| ▸ | PRKDC | P78527 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728352 | 0.85 | PIK3CD (0.34) | NSD2NSD3PIK3CDEPHB4LRRK2 | |
| SCHEMBL31728773 | 0.78 | CNR1 (0.32) | PIK3CDCNR2CNR1EPHB4PIK3CA | |
| SCHEMBL31728564 | 0.78 | CNR1 (0.32) | PIK3CDCNR2CNR1EPHB4PIK3CA | |
| SCHEMBL31727951 | 0.76 | DPP4 (0.33) | PIK3CDDPP4EPHB4PTPN11NUDT1 | |
| SCHEMBL31728959 | 0.76 | EPHB4 (0.36) | PIK3CDDPP4EPHB4PTPN11NUDT1 | |
| SCHEMBL31728454 | 0.76 | EIF2AK3 (0.36) | PIK3CDDPP4EPHB4PTPN11EIF2AK3 | |
| SCHEMBL31728885 | 0.74 | CNR2 (0.40) | NSD2NSD3PIK3CDCNR2CNR1 | |
| SCHEMBL31728468 | 0.73 | ERBB2 (0.37) | PIK3CDEPHB4PIK3CAPIK3CBPIK3CG | |
| SCHEMBL31728235 | 0.72 | SCN9A (0.35) | DPP4PTPN11EIF2AK3 | |
| SCHEMBL31728423 | 0.67 | DGAT1 (0.37) | PIK3CDPTPN11NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |