Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728886 | 0.87 | KDR (0.34) | EGFRERBB2KDR | |
| SCHEMBL31728385 | 0.84 | PIK3CD (0.35) | EGFRERBB2KDR | |
| SCHEMBL31727822 | 0.80 | EIF2AK3 (0.31) | — | |
| SCHEMBL31728351 | 0.80 | SRC (0.35) | EGFRKDR | |
| SCHEMBL31727918 | 0.77 | — | — | |
| SCHEMBL31727882 | 0.76 | ALOX5AP (0.32) | EGFRERBB2KDR | |
| SCHEMBL31728406 | 0.76 | PIK3CD (0.31) | EGFRKDR | |
| SCHEMBL31728454 | 0.74 | EIF2AK3 (0.36) | EGFRERBB2 | |
| SCHEMBL31728369 | 0.73 | KDR (0.34) | EGFRERBB2KDR | |
| SCHEMBL31728959 | 0.72 | EPHB4 (0.36) | EGFRERBB2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |