Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK4 | Q13043 | 6/20 | 0.44 |
| ▸ | STK3 | Q13188 | 6/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.44 |
| ▸ | ADK | P55263 | 3/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | ABL2 | P42684 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.35 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728532 | 0.84 | STK4 (0.52) | STK4STK3LRRK2ADKPDE10A | |
| SCHEMBL31729275 | 0.78 | STK4 (0.53) | STK4STK3LRRK2ADKPDE10A | |
| SCHEMBL31728927 | 0.74 | SRC (0.38) | ADKABL1EGFRSRCKDR | |
| SCHEMBL31728925 | 0.72 | SRC (0.37) | ADKPDE10AABL1EGFRSRC | |
| SCHEMBL31727887 | 0.69 | STK4 (0.53) | STK4STK3LRRK2ADKPDE10A | |
| SCHEMBL31728912 | 0.68 | NSD2 (0.35) | LRRK2CNR2 | |
| SCHEMBL31728043 | 0.68 | LRRK2 (0.31) | LRRK2ABL1EGFRSRCKDR | |
| SCHEMBL31728393 | 0.68 | SRC (0.37) | ADKABL1EGFRSRCKDR | |
| SCHEMBL31727905 | 0.66 | TBK1 (0.32) | CSNK1A1CSNK1DCSNK1ESRCKDR | |
| SCHEMBL31728130 | 0.66 | SRC (0.45) | STK4STK3ADKABL1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |