Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 4/20 | 0.70 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.70 |
| ▸ | PDK3 | Q15120 | 4/20 | 0.70 |
| ▸ | PDK4 | Q16654 | 4/20 | 0.70 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.52 |
| ▸ | PGR | P06401 | 3/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | SHBG | P04278 | 2/20 | 0.48 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.48 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3444251 | 1.00 | PDK1 (0.70) | PDK1PDK2PDK3PDK4NR1I2 | |
| SCHEMBL13770133 | 0.85 | PDK1 (0.57) | PDK1PDK2PDK3PDK4NR1I2 | |
| SCHEMBL5173777 | 0.85 | NR1I2 (0.62) | PDK1PDK2PDK3PDK4NR1I2 | |
| SCHEMBL5173779 | 0.85 | NR1I2 (0.62) | PDK1PDK2PDK3PDK4NR1I2 | |
| SCHEMBL12446091 | 0.84 | SHBG (0.69) | SLC6A4PGRNR3C1SHBGSERPINA6 | |
| SCHEMBL5076704 | 0.84 | SHBG (0.69) | SLC6A4PGRNR3C1SHBGSERPINA6 | |
| SCHEMBL4437111 | 0.84 | SHBG (0.69) | SLC6A4PGRNR3C1SHBGSERPINA6 | |
| SCHEMBL6841786 | 0.82 | PDK1 (1.00) | PDK1PDK2PDK3PDK4NR1I2 | |
| SCHEMBL8467502 | 0.79 | PGR (0.56) | PDK1PDK2PDK3PDK4NR1I2 | |
| SCHEMBL9197781 | 0.78 | ESR1 (0.60) | PDK1PDK2PDK3PDK4NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816546-B2 | Process for the synthesis of high purity d-(17α)-13-ethyl-17-hydroxy-18,19-dinorpregn-4-ene-20-yn-3-one-oxime | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2010-10-19 | — | — | US | disclosed |
| EP-1638988-B1 | PROCESS FOR THE SYNTHESIS OF HIGH PURITY D-(17ALPHA)-13-ETHYL-17HYDROXY-18,19-DINORPRE:GN-4-ENE-20-YNE-3-ONE-OXIME | RICHTER GEDEON NYRT (HU) | 2010-03-31 | — | — | EP | disclosed |
| EP-1638988-A1 | PROCESS FOR THE SYNTHESIS OF HIGH PURITY D-(17ALPHA)-13-ETHYL-17HYDROXY-18,19-DINORPRE:GN-4-ENE-20-YNE-3-ONE-OXIME | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 2006-03-29 | — | — | EP | disclosed |
| US-20050032763-A1 | Process for the synthesis of high purity D-(17a)-13-ethyl-17-hydroxy-18,19-dinorpregn-4-ene-20-yn-3-one oxime | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2005-02-10 | — | — | US | disclosed |
| WO-2005000868-A1 | PROCESS FOR THE SYNTHESIS OF HIGH PURITY D-(17ALPHA)-13-ETHYL-17HYDROXY-18,19-DINORPRE:GN-4-ENE-20-YNE-3-ONE-OXIME | RICHTER GEDEON VEGYÉSZETI GYÁR R.T. (HU) | 2005-01-06 | — | — | WO | disclosed |