Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 5/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.56 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
| ▸ | PDK1 | Q15118 | 4/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.50 |
| ▸ | PDK3 | Q15120 | 4/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 4/20 | 0.50 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | AR | P10275 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4885223 | 0.86 | PDK1 (0.63) | PGRNR3C1SLC6A4NR1I2ADORA3 | |
| SCHEMBL5173777 | 0.84 | NR1I2 (0.62) | PGRNR3C1SLC6A4NR1I2ADORA3 | |
| SCHEMBL5173779 | 0.84 | NR1I2 (0.62) | PGRNR3C1SLC6A4NR1I2ADORA3 | |
| SCHEMBL3444251 | 0.79 | PDK1 (0.70) | PGRNR3C1SLC6A4NR1I2ADORA3 | |
| SCHEMBL3173361 | 0.79 | PDK1 (0.70) | PGRNR3C1SLC6A4NR1I2ADORA3 | |
| SCHEMBL13770133 | 0.74 | PDK1 (0.57) | PGRNR3C1SLC6A4NR1I2ADORA3 | |
| SCHEMBL354932 | 0.73 | PGR (0.49) | PGRNR3C1SLC6A4NR1I2ADORA3 | |
| SCHEMBL11861302 | 0.73 | PGR (0.52) | PGRNR3C1SLC6A4SERPINA6MEN1 | |
| SCHEMBL3677252 | 0.73 | PGR (0.59) | PGRNR3C1SLC6A4NR1I2ADORA3 | |
| Norgestimate SCHEMBL5523236 | 0.72 | PGR (1.00) | PGRNR3C1SLC6A4NR1I2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994292-A | POLYPEPTIDE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1999-11-30 | — | — | US | disclosed |