Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC8 | Q09428 | 3/20 | 0.51 |
| ▸ | KCNJ11 | Q14654 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL718487 | 0.87 | ABCC8 (0.56) | ABCC8KCNJ11ALDH1A1CYP1A2LMNA | |
| SCHEMBL24050507 | 0.85 | ABCC8 (0.53) | ABCC8KCNJ11ALDH1A1CYP1A2LMNA | |
| SCHEMBL6555285 | 0.85 | ABCC8 (0.53) | ABCC8KCNJ11ALDH1A1CYP1A2LMNA | |
| SCHEMBL31734795 | 0.84 | ALDH1A1 (0.33) | ABCC8KCNJ11ALDH1A1CYP1A2LMNA | |
| SCHEMBL717798 | 0.84 | ABCC8 (0.52) | ABCC8KCNJ11ALDH1A1CYP1A2LMNA | |
| SCHEMBL31734762 | 0.80 | ABCC8 (0.48) | ABCC8KCNJ11ALDH1A1CYP1A2LMNA | |
| SCHEMBL31734796 | 0.79 | ABCC8 (0.55) | ABCC8KCNJ11ALDH1A1CYP1A2LMNA | |
| SCHEMBL718174 | 0.78 | ABCC8 (0.44) | ABCC8KCNJ11ALDH1A1CYP1A2LMNA | |
| SCHEMBL6553120 | 0.76 | ABCC8 (0.48) | ABCC8KCNJ11ALDH1A1CYP1A2LMNA | |
| SCHEMBL24050255 | 0.76 | ABCC8 (0.45) | ABCC8KCNJ11ALDH1A1CYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250360142-A1 | NOVEL ATP-SENSITIVE POTASSIUM CHANNEL POTENTIATORS, THEIR PREPARATION AND USE | RHYTHM PHARMACEUTICALS INC (US) | 2025-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250360142-A1 | NOVEL ATP-SENSITIVE POTASSIUM CHANNEL POTENTIATORS, THEIR PREPARATION AND USE | KCNJ11, ATP1A2, ATP1A3 | ABCC8 95/4885KCNJ11 1/4885ALDH1A1 2043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.