Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31735660 | 0.84 | ALDH1A1 (0.49) | HPGDBRD4BRD9SMN1; SMN2ADORA2A | |
| SCHEMBL25099090 | 0.83 | CYP11B2 (0.55) | HPGDRXRARXRBBRD4SMN1; SMN2 | |
| SCHEMBL12263261 | 0.72 | HPGD (0.44) | HPGDMAP4K4CHEK1ADORA2AADORA2B | |
| SCHEMBL28376237 | 0.70 | ALDH1A1 (0.56) | RXRARXRBSMN1; SMN2MAP4K4ALDH1A1 | |
| SCHEMBL18420453 | 0.69 | AKT1 (0.46) | HPGDRXRARXRBMAP4K4CHEK1 | |
| SCHEMBL18420397 | 0.69 | AKT1 (0.48) | HPGDRXRARXRBMAP4K4CHEK1 | |
| SCHEMBL30620654 | 0.69 | CYP11B2 (0.54) | BRD4BRD9MAP4K4CREBBPCYP11B2 | |
| SCHEMBL3330685 | 0.68 | GPR119 (0.46) | HPGDRXRARXRBSMN1; SMN2RAB9A | |
| SCHEMBL12263289 | 0.67 | HPGD (0.46) | HPGDRXRARXRBSMN1; SMN2ALDH1A1 | |
| SCHEMBL24369883 | 0.67 | CYP11B2 (0.51) | HPGDBRD4SMN1; SMN2ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025245484-A1 | FOXN1 ACTIVATORS | THYMOFOX INC. (US) | 2025-11-27 | — | — | WO | disclosed |