Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 6/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 5/20 | 0.38 |
| ▸ | LDHA | P00338 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 2/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25297947 | 0.80 | KMT2A (0.37) | CYP11B1CYP11B2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1289901 | 0.78 | CYP11B1 (0.54) | CYP11B1CYP11B2LDHANPC1RAB9A | |
| SCHEMBL6260766 | 0.75 | CYP11B1 (0.46) | CYP11B1CYP11B2KDM1ANPC1RAB9A | |
| SCHEMBL7452982 | 0.73 | CYP11B2 (0.42) | CYP11B1CYP11B2FLT3 | |
| SCHEMBL31716086 | 0.73 | LDHA (0.51) | CYP11B1CYP11B2LDHANPC1TP53 | |
| SCHEMBL19072737 | 0.73 | GRM5 (0.47) | KDM1AGRM5LDHANPC1MET | |
| SCHEMBL1772141 | 0.72 | KIF11 (0.41) | CYP11B1NPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL7107602 | 0.71 | CCR1 (0.57) | CYP11B1CYP11B2GRM5NPC1TP53 | |
| SCHEMBL1019992 | 0.70 | KDM4E (0.43) | CYP11B1CYP11B2 | |
| SCHEMBL2322693 | 0.68 | LDHA (0.55) | KDM1ALDHANPC1TP53PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025245472-A1 | COMPOUNDS AND RELATED METHODS USEFUL FOR DEGRADATION OF CYCLIN K AND INHIBITION OF CYCLIN DEPENDENT KINASES | REMIX THERAPEUTICS INC. (US) | 2025-11-27 | — | — | WO | disclosed |