SCHEMBL31735690

SCHEMBL31735690

CC(=O)N1CCC(CCn2ccc3c(Br)c(Cl)ccc32)CC1

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NR3C1 P04150 1/20 0.38
▸ OPRL1 P41146 1/20 0.36
▸ TGFBR1 P36897 1/20 0.36
▸ CCR5 P51681 1/20 0.35
▸ PKM P14618 1/20 0.35
▸ DRD2 P14416 1/20 0.35
▸ DRD3 P35462 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31735468 0.86 KDM4E (0.42) PKM
SCHEMBL31735567 0.75 NR3C1 (0.38) NR3C1PKM
SCHEMBL31735527 0.74 NOTUM (0.37) —
SCHEMBL2369606 0.70 FNTA (0.36) —
SCHEMBL6411333 0.69 HTR1A (0.52) OPRL1DRD3
SCHEMBL31735812 0.69 STS (0.43) PKM
SCHEMBL14321953 0.68 FNTA (0.39) —
SCHEMBL31735638 0.68 DYRK1A (0.36) —
SCHEMBL31735634 0.67 NR3C1 (0.38) NR3C1PKM
SCHEMBL31735374 0.67 KDM4E (0.41) PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
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