SCHEMBL31735812

SCHEMBL31735812

CC(C)(C)OC(=O)N1CCC(CCn2ccc3c(Br)cc(Cl)cc32)CC1

nearest known ligand 0.48

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ STS P08842 2/20 0.43
▸ KDM4E B2RXH2 1/20 0.41
▸ PKM P14618 1/20 0.41
▸ GPR119 Q8TDV5 6/20 0.41
▸ CNR1 P21554 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31735374 0.84 KDM4E (0.41) KDM4EPKMGPR119
SCHEMBL31735468 0.83 KDM4E (0.42) STSKDM4EPKMGPR119
SCHEMBL31735699 0.78 PIK3CA (0.39) STSGPR119
SCHEMBL20476727 0.77 GPR119 (0.43) KDM4EPKMGPR119
SCHEMBL26116198 0.76 HTR6 (0.48) KDM4EPKMGPR119
SCHEMBL15521929 0.75 ALDH1A1 (0.45) KDM4EPKMGPR119
SCHEMBL4002091 0.73 GPR119 (0.48) KDM4EPKMGPR119
SCHEMBL15522269 0.72 ALDH1A1 (0.48) GPR119
SCHEMBL27150006 0.71 STS (0.45) STSKDM4EPKMGPR119
SCHEMBL4002013 0.71 GPR119 (0.44) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
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