SCHEMBL31735567

SCHEMBL31735567

CC(=O)N1CCC(CCn2ccc3c(Nc4cnn(C)c(=O)c4C)c(Cl)ccc32)CC1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ NR3C1 P04150 1/20 0.38
▸ JAK2 O60674 1/20 0.37
▸ JAK1 P23458 1/20 0.37
▸ TYK2 P29597 1/20 0.37
▸ JAK3 P52333 1/20 0.37
▸ BRD9 Q9H8M2 7/20 0.36
▸ BRD4 O60885 6/20 0.36
▸ BPTF Q12830 1/20 0.36
▸ PKM P14618 1/20 0.35
▸ BRPF1 P55201 1/20 0.35
▸ BRD7 Q9NPI1 1/20 0.35
▸ LRRK2 Q5S007 1/20 0.34
▸ IGF1R P08069 2/20 0.34
▸ CDK2 P24941 2/20 0.34
▸ PDE4A P27815 1/20 0.34
▸ PDE4B Q07343 1/20 0.34
▸ PDE4C Q08493 1/20 0.34
▸ PDE4D Q08499 1/20 0.34
▸ KCNH2 Q12809 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31735634 0.87 NR3C1 (0.38) NR3C1JAK2JAK1TYK2JAK3
SCHEMBL31735743 0.84 NR3C1 (0.38) NR3C1JAK2JAK1TYK2JAK3
SCHEMBL31735484 0.81 LRRK2 (0.37) BRD9BRD4BPTFBRPF1BRD7
SCHEMBL31735746 0.79 BRD4 (0.42) BRD9BRD4BPTFBRPF1BRD7
SCHEMBL31735635 0.77 BPTF (0.46) NR3C1BRD9BRD4BPTFBRD7
SCHEMBL31735699 0.77 PIK3CA (0.39) NR3C1BRD4
SCHEMBL31735690 0.75 NR3C1 (0.38) NR3C1PKM
SCHEMBL31735869 0.75 PIK3CA (0.39) BRD4
SCHEMBL31735640 0.73 BRD9 (0.41) BRD9BRD4BPTFBRPF1BRD7
SCHEMBL31735427 0.72 BRD9 (0.42) BRD9BRD4BPTFBRPF1BRD7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
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