Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | FABP1 | P07148 | 1/20 | 0.55 |
| ▸ | FABP6 | P51161 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NOS2 | P35228 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23409086 | 0.83 | CYP1A2 (0.52) | L3MBTL1NPC1RAB9ANPSR1HSD17B10 | |
| SCHEMBL2464554 | 0.82 | NPC1 (1.00) | L3MBTL1NPC1RAB9ANPSR1HSD17B10 | |
| SCHEMBL2128197 | 0.82 | MEN1 (0.62) | L3MBTL1NPC1RAB9ANPSR1HSD17B10 | |
| SCHEMBL19180705 | 0.80 | ALDH1A1 (0.56) | L3MBTL1NPC1RAB9ANPSR1HSD17B10 | |
| SCHEMBL11447670 | 0.78 | FABP1 (0.55) | L3MBTL1NPSR1HSD17B10KDM4EALDH1A1 | |
| SCHEMBL12820608 | 0.78 | FABP1 (0.55) | L3MBTL1NPSR1KDM4EALDH1A1HPGD | |
| SCHEMBL23751303 | 0.78 | FABP1 (0.55) | L3MBTL1KDM4EALDH1A1HPGDFABP1 | |
| SCHEMBL31240581 | 0.78 | FABP1 (0.55) | L3MBTL1KDM4EALDH1A1HPGDFABP1 | |
| SCHEMBL18809821 | 0.77 | HDAC1 (0.57) | HSD17B10KDM4EALDH1A1HPGDFABP1 | |
| SCHEMBL4856968 | 0.77 | KDM4E (0.49) | L3MBTL1NPC1RAB9ANPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9422375-B2 | Non-cyclopentadienyl-based chromium catalysts for olefin polymerization | DOW GLOBAL TECHNOLOGIES LLC | 2016-08-23 | — | — | US | claimed |
| US-9296836-B2 | Non-cyclopentadienyl-based chromium catalysts for olefin polymerization | DOW GLOBAL TECHNOLOGIES LLC | 2016-03-29 | — | — | US | claimed |
| US-20160053031-A1 | NON-CYCLOPENTADIENYL-BASED CHROMIUM CATALYSTS FOR OLEFIN POLYMERIZATION | DOW GLOBAL TECHNOLOGIES LLC | 2016-02-25 | — | — | US | claimed |
| US-20150148502-A1 | NON-CYCLOPENTADIENYL-BASED CHROMIUM CATALYSTS FOR OLEFIN POLYMERIZATION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-05-28 | — | — | US | claimed |
| US-11685732-B2 | MYST family histone acetyltransferase inhibitors | Epizyme, Inc. (US) | 2023-06-27 | — | — | US | disclosed |
| US-11685732-B2 | MYST family histone acetyltransferase inhibitors | Epizyme, Inc. (US) | 2023-06-27 | — | — | US | disclosed |
| US-20180207628-A1 | OXALIC ACID MONOAMIDE LIGAND, AND USES THEREOF IN COUPLING REACTION OF COPPER-CATALYZED ARYL HALOGEN SUBSTITUTE | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2018-07-26 | — | — | US | disclosed |
| US-20180207628-A1 | OXALIC ACID MONOAMIDE LIGAND, AND USES THEREOF IN COUPLING REACTION OF COPPER-CATALYZED ARYL HALOGEN SUBSTITUTE | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2018-07-26 | — | — | US | disclosed |
| EP-3326715-A1 | OXALIC ACID MONOAMIDE LIGAND, AND USES THEREOF IN COUPLING REACTION OF COPPER-CATALYZED ARYL HALOGEN SUBSTITUTE | Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CN) | 2018-05-30 | — | — | EP | disclosed |
| WO-2017012379-A1 | OXALIC ACID MONOAMIDE LIGAND, AND USES THEREOF IN COUPLING REACTION OF COPPER-CATALYZED ARYL HALOGEN SUBSTITUTE | 中国科学院上海有机化学研究所 | 2017-01-26 | — | — | WO | disclosed |
| US-9422375-B2 | Non-cyclopentadienyl-based chromium catalysts for olefin polymerization | DOW GLOBAL TECHNOLOGIES LLC | 2016-08-23 | — | — | US | disclosed |
| US-9422375-B2 | Non-cyclopentadienyl-based chromium catalysts for olefin polymerization | DOW GLOBAL TECHNOLOGIES LLC | 2016-08-23 | — | — | US | disclosed |
| US-7282498-B2 | Substituted fused pyrroleoximes and fused pyrazoleoximes | NEUROGEN CORPORATION (US) | 2007-10-16 | — | — | US | disclosed |
| US-20070072096-A1 | Negative curable dye-containing composition, color filter, and method of manufacturing the same | FUJI PHOTO FILM CO., LTD. | 2007-03-29 | — | — | US | disclosed |
| EP-1764366-A2 | Thrombin receptor antagonists | SCHERING CORPORATION (US) | 2007-03-21 | — | — | EP | disclosed |
| US-20050227290-A1 | Novel coordination complexes, and methods for preparing by combinatorial methods, assaying and using the same | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-10-13 | — | — | US | disclosed |
| US-6806289-B1 | SUCH AS AMMINE (2-AMINO-3-PICOLINE) DICHLOROPLATINUM(II); EFFICIENCY AND SELECTIVITY FOR DESTROYING TRANSFORMED CELLS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-10-19 | — | — | US | disclosed |
| US-6210816-B1 | Translucent xerographic recording substrates | XEROX CORPORATION | 2001-04-03 | — | — | US | disclosed |
| EP-0376870-A1 | A new organosilylpolyphosphoric reagent, its preparation and application to the process of synthesis of 3-carboxyquinolones or azaquinolones and their salts | CENTRO MARGA PARA LA INVESTIGACION S.A. (ES) | 1990-07-04 | — | — | EP | disclosed |
| EP-0000816-A1 | Substituted amino-pyridine derivatives, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1979-02-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150148502-A1 | NON-CYCLOPENTADIENYL-BASED CHROMIUM CATALYSTS FOR OLEFIN POLYMERIZATION | CRKL, HCK, CCRL2 | L3MBTL1 1324/4885NPC1 3984/4885RAB9A 1976/4885 |
| US-11685732-B2 | MYST family histone acetyltransferase inhibitors | EP300, KAT2A, KAT6A | L3MBTL1 693/4885NPC1 329/4885RAB9A 2422/4885 |
| US-20160053031-A1 | NON-CYCLOPENTADIENYL-BASED CHROMIUM CATALYSTS FOR OLEFIN POLYMERIZATION | CRKL, HCK, CCRL2 | L3MBTL1 1324/4885NPC1 3984/4885RAB9A 1976/4885 |
| US-20180207628-A1 | OXALIC ACID MONOAMIDE LIGAND, AND USES THEREOF IN COUPLING REACTION OF COPPER-CATALYZED ARYL HALOGEN SUBSTITUTE | AOC2, AOC1, AOC3 | L3MBTL1 4763/4885NPC1 4654/4885RAB9A 4192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.