SCHEMBL31742329

SCHEMBL31742329

COC(=O)c1ccc(-c2nc(-c3ccc(N(C)C)cc3)c(-c3ccccc3)[nH]2)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAF1 P04049 2/20 0.76
NOX1 Q9Y5S8 2/20 0.73
KDM4E B2RXH2 4/20 0.61
ALDH1A1 P00352 4/20 0.61
HPGD P15428 4/20 0.61
KMT2A Q03164 4/20 0.61
GLA P06280 3/20 0.61
GAA P10253 3/20 0.61
MEN1 O00255 3/20 0.61
MAPT P10636 3/20 0.61
CYP1A2 P05177 1/20 0.61
CYP2C19 P33261 1/20 0.61
GFER P55789 1/20 0.61
MAPK14 Q16539 3/20 0.61
ALOX5 P09917 2/20 0.61
MAPK13 O15264 2/20 0.61
MAPK12 P53778 2/20 0.61
MAPK11 Q15759 2/20 0.61
GCGR P47871 1/20 0.61
IDO1 P14902 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30762099 1.00 RAF1 (0.76) RAF1NOX1KDM4EALDH1A1HPGD
SCHEMBL8797140 0.95 RAF1 (0.67) RAF1NOX1KDM4EALDH1A1HPGD
SCHEMBL4552086 0.92 RAF1 (0.88) RAF1NOX1KDM4EALDH1A1HPGD
SCHEMBL1071183 0.85 NOX1 (1.00) RAF1NOX1KDM4EALDH1A1HPGD
SCHEMBL8797410 0.84 NOX1 (0.72) RAF1NOX1KDM4EALDH1A1HPGD
SCHEMBL4551697 0.79 NOX1 (0.72) RAF1NOX1KDM4EALDH1A1HPGD
SCHEMBL12180841 0.79 RAF1 (0.68) RAF1NOX1KDM4EALDH1A1HPGD
SCHEMBL4721236 0.79 RAF1 (0.72) RAF1KDM4EALDH1A1HPGDKMT2A
SCHEMBL14336058 0.78 NOX1 (0.78) RAF1NOX1KDM4EALDH1A1HPGD
SCHEMBL14601534 0.78 RAF1 (0.66) RAF1NOX1KDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250377364-A1 REAGENT, METHOD, AND DEVICE FOR DETECTING ALBUMIN NEC CORPORATION (JP) 2025-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250377364-A1 REAGENT, METHOD, AND DEVICE FOR DETECTING ALBUMIN ALB, TTR, MTTP RAF1 2168/4885NOX1 3707/4885KDM4E 4715/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.