Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5004053 | 0.80 | RAPGEF4 (0.43) | ALDH1A1TSHRHSD17B10CYP3A4RECQL | |
| SCHEMBL10507454 | 0.73 | NMT1 (0.48) | ALDH1A1TSHRCYP3A4AHRTDP1 | |
| SCHEMBL3747036 | 0.73 | CES2 (0.33) | HPGDCA1CA9CES1 | |
| SCHEMBL1805217 | 0.73 | TSHR (0.36) | ALDH1A1TSHRHSD17B10HPGDMEN1 | |
| SCHEMBL22632969 | 0.73 | CYP3A4 (0.58) | ALDH1A1TSHRHSD17B10CYP3A4RECQL | |
| SCHEMBL2937097 | 0.72 | TSHR (0.67) | ALDH1A1TSHRHSD17B10CYP3A4RECQL | |
| SCHEMBL6378496 | 0.72 | AKR1C4 (0.45) | ALDH1A1TSHRHSD17B10CYP3A4RECQL | |
| SCHEMBL1810206 | 0.72 | CA1 (0.47) | ALDH1A1TSHRHSD17B10CYP3A4RECQL | |
| SCHEMBL1804696 | 0.72 | CA1 (0.62) | CA1CA2CA9TDP1LMNA | |
| SCHEMBL5961682 | 0.71 | ALDH1A1 (0.61) | ALDH1A1TSHRHSD17B10CYP3A4RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 290 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897560-B2 | Plasma protein affinity tags | NOVO NORDISK A/S (DK) | 2011-03-01 | — | — | US | claimed |
| US-20100184641-A1 | Novel Plasma Protein Affinity Tags | NOVO NORDISK A/S (DK) | 2010-07-22 | — | — | US | claimed |
| US-7547749-B2 | Triazine compounds, polymers comprising triazine structural units, and method | SABIC INNOVATIVE PLATICS IP B.V. (NL) | 2009-06-16 | — | — | US | claimed |
| US-20080097040-A1 | TRIAZINE COMPOUNDS, POLYMERS COMPRISING TRIAZINE STRUCTURAL UNITS, AND METHOD | GENERAL ELECTRIC COMPANY (US) | 2008-04-24 | — | — | US | claimed |
| US-20070105750-A1 | Novel plasma protein affinity tags | NOVO NORDISK A/S (DK) | 2007-05-10 | — | — | US | claimed |
| EP-1667724-A2 | ALBUMIN-BINDING DERIVATIVES OF THERAPEUTIC PEPTIDES | NOVO NORDISK A/S (DK) | 2006-06-14 | — | — | EP | claimed |
| US-20050192411-A1 | Triazine compounds, polymers comprising triazine structural units, and method | GENERAL ELECTRIC CO. | 2005-09-01 | — | — | US | claimed |
| EP-1066269-B1 | TRISUBSTITUTED 1,3,5-TRIAZINE DERIVATIVES FOR TREATMENT OF HIV INFECTIONS | JANSSEN PHARMACEUTICA NV (BE) | 2005-05-11 | — | — | EP | claimed |
| WO-2005028516-A2 | ALBUMIN-BINDING DERIVATIVES OF THERAPEUTIC PEPTIDES | NOVO NORDISK A/S (DK) | 2005-03-31 | — | — | WO | claimed |
| EP-1423372-A2 | TRIAZINE COMPOUNDS, POLYMERS COMPRISING TRIAZINE STRUCTURAL UNITS, AND PROCESSES FOR THE PREPARATION OF THESE POLYMERS | GENERAL ELECTRIC COMPANY (US) | 2004-06-02 | — | — | EP | claimed |
| EP-1066269-A1 | TRISUBSTITUTED 1,3,5-TRIAZINE DERIVATIVES FOR TREATMENT OF HIV INFECTIONS | JANSSEN PHARMACEUTICA N.V. (BE) | 2001-01-10 | — | — | EP | claimed |
| US-6150360-A | ADMINISTERING TO A PATIENT SUFFERING FROM HUMAN IMMUNODEFICIENCY VIRUS INFECTION A TRISUBSTITUTED 1,3,5-TRIAZINE DERIVATIVE | JANSSEN PHARMACEUTICA N.V. (BE) | 2000-11-21 | — | — | US | claimed |
| WO-1999050256-A1 | TRISUBSTITUTED 1,3,5-TRIAZINE DERIVATIVES FOR TREATMENT OF HIV INFECTIONS | JANSSEN PHARMACEUTICA N.V. (BE) | 1999-10-07 | — | — | WO | claimed |
| EP-0583806-B1 | Acrylic derivatives of 2-thiazolypyrroles having a fungicidal activity | MINI RICERCA SCIENT TECNOLOG (IT) | 1997-10-15 | — | — | EP | claimed |
| EP-0554956-B1 | Thiazolylpyrroles having a fungicidal activity | MINI RICERCA SCIENT TECNOLOG (IT) | 1997-10-01 | — | — | EP | claimed |
| EP-0583806-A1 | Acrylic derivatives of 2-thiazolypyrroles having a fungicidal activity | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1994-02-23 | — | — | EP | claimed |
| US-5241084-A | PREPARATION PROCESS OF GINKGOLIDE B FROM GINKGOLIDE C | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1993-08-31 | — | — | US | claimed |
| EP-0554956-A1 | Thiazolylpyrroles having a fungicidal activity | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1993-08-11 | — | — | EP | claimed |
| US-4579684-A | Process for the manufacture of enol derivatives | CIBA-GEIGY CORPORATION (US) | 1986-04-01 | — | — | US | claimed |
| US-4293462-A | Process for the manufacture of enol derivatives, and intermediates | CIBA-GEIGY CORPORATION (US) | 1981-10-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184641-A1 | Novel Plasma Protein Affinity Tags | CD2BP2, HDLBP, SERPINA6 | ALDH1A1 4651/4885TSHR 1995/4885HSD17B10 3288/4885 |
| US-20070105750-A1 | Novel plasma protein affinity tags | CD2BP2, HDLBP, SERPINA6 | ALDH1A1 4651/4885TSHR 1995/4885HSD17B10 3288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.