SCHEMBL31744698

SCHEMBL31744698

COc1ccc(Oc2c[nH]c3ccc(Br)cc23)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.49
HTR1A P08908 3/20 0.48
TUBB4A P04350 1/20 0.48
TUBB P07437 1/20 0.48
TUBA3C P0DPH7 1/20 0.48
TUBA1B P68363 1/20 0.48
TUBA4A P68366 1/20 0.48
TUBB4B P68371 1/20 0.48
TUBB3 Q13509 1/20 0.48
TUBB2A Q13885 1/20 0.48
TUBB8 Q3ZCM7 1/20 0.48
TUBA3E Q6PEY2 1/20 0.48
TUBA1A Q71U36 1/20 0.48
TUBA1C Q9BQE3 1/20 0.48
TUBB6 Q9BUF5 1/20 0.48
TUBB2B Q9BVA1 1/20 0.48
TUBB1 Q9H4B7 1/20 0.48
NR4A2 P43354 2/20 0.48
GPR84 Q9NQS5 2/20 0.45
EGFR P00533 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31744585 0.91 GPR84 (0.53) HTR1ATUBB4ATUBBTUBA3CTUBA1B
SCHEMBL31744595 0.91 GPR84 (0.50) IDO1HTR1ATUBB4ATUBBTUBA3C
SCHEMBL31744721 0.87 IDO1 (0.49) IDO1HTR1ATUBB4ATUBBTUBA3C
SCHEMBL31744648 0.85 HTR1A (0.45) IDO1HTR1ATUBB4ATUBBTUBA3C
SCHEMBL31744839 0.85 MAPT (0.49) IDO1HTR1ATUBB4ATUBBTUBA3C
SCHEMBL31744859 0.85 RHEB (0.47) IDO1HTR1ATUBB4ATUBBTUBA3C
SCHEMBL31744596 0.84 IDO1 (0.48) IDO1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL12713875 0.84 IDO1 (0.60) IDO1HTR1ATUBB4ATUBBTUBA3C
SCHEMBL31744817 0.83 GPR84 (0.50) IDO1HTR1ATUBB4ATUBBTUBA3C
SCHEMBL31744768 0.82 SCN9A (0.44) IDO1NR4A2GPR84HTR2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250382268-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CFD RES CORPORATION (US) 2025-12-18 US claimed
US-20250382268-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CFD RES CORPORATION (US) 2025-12-18 US disclosed
US-20250382269-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CFD RES CORPORATION (US) 2025-12-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250382269-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CD14, MIF, NOD2 IDO1 38/4885HTR1A 4485/4885TUBB4A 2340/4885
US-20250382268-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CD14, MIF, NOD2 IDO1 38/4885HTR1A 4485/4885TUBB4A 2340/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.