SCHEMBL31744871

SCHEMBL31744871

Brc1ccc(Cc2c[nH]c3c(Br)cc(Br)cc23)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 3/20 0.47
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
HTR6 P50406 1/20 0.36
HTR2A P28223 1/20 0.36
TRPM8 Q7Z2W7 1/20 0.36
HRH3 Q9Y5N1 1/20 0.36
CSNK2A1 P68400 1/20 0.36
PDE3B Q13370 1/20 0.35
PDE3A Q14432 1/20 0.35
MTNR1A P48039 2/20 0.34
MTNR1B P49286 2/20 0.34
CHRNB2 P17787 1/20 0.34
CHRNA7 P36544 1/20 0.34
CHRNA4 P43681 1/20 0.34
USP2 O75604 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
ALOX15 P16050 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31744761 0.81 GPR84 (0.47) GPR84MEN1KMT2AHTR6HTR2A
SCHEMBL31744785 0.77 GPR84 (0.80) GPR84MEN1KMT2AHTR6HTR2A
SCHEMBL31744618 0.75 GPR84 (0.57) GPR84MEN1KMT2AHTR6HTR2A
SCHEMBL31744771 0.74 GPR84 (0.44) GPR84MEN1KMT2AHTR6HTR2A
SCHEMBL9407213 0.73 HTR2A (0.57) HTR6HTR2ATRPM8MTNR1AMTNR1B
SCHEMBL31744675 0.73 CHRNB2 (0.60) GPR84MEN1KMT2AHTR6HTR2A
Hydrochloric Acid SCHEMBL7816372 0.72 HTR2A (0.55) KMT2AHTR6HTR2ATRPM8MAPT
SCHEMBL31744816 0.71 CSNK2A1 (0.57) GPR84MEN1KMT2AHTR6HTR2A
SCHEMBL28781646 0.70 MEN1 (0.74) GPR84MEN1KMT2AHTR6HTR2A
SCHEMBL3407856 0.69 GPR84 (0.71) GPR84MEN1KMT2AHTR6HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250382268-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CFD RES CORPORATION (US) 2025-12-18 US claimed
US-20250382269-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CFD RES CORPORATION (US) 2025-12-18 US disclosed
US-20250382268-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CFD RES CORPORATION (US) 2025-12-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250382269-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CD14, MIF, NOD2 GPR84 4183/4885MEN1 2402/4885KMT2A 4633/4885
US-20250382268-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CD14, MIF, NOD2 GPR84 4183/4885MEN1 2402/4885KMT2A 4633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.