SCHEMBL31744882

SCHEMBL31744882

c1ccc(Nc2c[nH]c3ccccc23)nc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 3/20 0.56
▸ KMT2A Q03164 3/20 0.56
▸ MAPK10 P53779 1/20 0.56
▸ GFER P55789 1/20 0.56
▸ MAPT P10636 4/20 0.54
▸ ATM Q13315 2/20 0.54
▸ GAA P10253 1/20 0.54
▸ TDP1 Q9NUW8 1/20 0.54
▸ LMNA P02545 3/20 0.48
▸ ALDH1A1 P00352 2/20 0.48
▸ NPC1 O15118 2/20 0.46
▸ RAB9A P51151 2/20 0.46
▸ HPGD P15428 1/20 0.46
▸ ALOX15 P16050 1/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.46
▸ APAF1 O14727 1/20 0.42
▸ TDP2 O95551 1/20 0.42
▸ CDC25B P30305 1/20 0.42
▸ CASP6 P55212 1/20 0.42
▸ RCE1 Q9Y256 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7336890 1.00 MEN1 (0.56) MEN1KMT2AMAPK10GFERMAPT
SCHEMBL14185394 0.83 FLT3 (0.50) MEN1KMT2AMAPTATMGAA
SCHEMBL6654114 0.80 ATM (0.52) MEN1KMT2AMAPTATMTDP1
SCHEMBL22725717 0.75 CHEK1 (0.43) PIM1FLT3MKNK1MKNK2
SCHEMBL5618628 0.75 IMPDH2 (0.53) MEN1KMT2AMAPTATMGAA
SCHEMBL29439082 0.74 IGF1R (0.42) MEN1KMT2AMAPTATMTDP1
SCHEMBL22717761 0.74 IGF1R (0.42) MEN1KMT2AMAPTATMTDP1
SCHEMBL22717769 0.74 CLK1 (0.40) KMT2AMAPTATMGAATDP1
SCHEMBL29439041 0.74 CLK1 (0.40) KMT2AMAPTATMGAATDP1
SCHEMBL3279571 0.73 MEN1 (1.00) MEN1KMT2AMAPK10GFERGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250382268-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CFD RES CORPORATION (US) 2025-12-18 — — US claimed
US-20250382268-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CFD RES CORPORATION (US) 2025-12-18 — — US disclosed
US-20250382269-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CFD RES CORPORATION (US) 2025-12-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250382269-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CD14, MIF, NOD2 MEN1 2402/4885KMT2A 4633/4885MAPK10 1044/4885
US-20250382268-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CD14, MIF, NOD2 MEN1 2402/4885KMT2A 4633/4885MAPK10 1044/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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