SCHEMBL31747481

SCHEMBL31747481

CC(C)(C)OC(=O)N1CCC(CCCn2cc(-c3cccc(C(N)=O)c3)cn2)CC1

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 12/20 0.48
▸ CHEK2 O96017 3/20 0.46
▸ KDM4E B2RXH2 1/20 0.45
▸ PKM P14618 1/20 0.45
▸ IRAK1 P51617 1/20 0.45
▸ FAAH O00519 1/20 0.44
▸ PARP14 Q460N5 1/20 0.42
▸ USP30 Q70CQ3 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31747263 0.92 GPR119 (0.49) GPR119KDM4EPKMIRAK1FAAH
SCHEMBL31747452 0.90 GPR119 (0.47) GPR119KDM4EPKMIRAK1FAAH
SCHEMBL31173852 0.89 GPR119 (0.58) GPR119CHEK2USP30
SCHEMBL31747273 0.85 GPR119 (0.50) GPR119CHEK2KDM4EPKMFAAH
SCHEMBL31752792 0.84 GPR119 (0.49) GPR119CHEK2FAAHUSP30
SCHEMBL31753579 0.83 GPR119 (0.49) GPR119CHEK2FAAHUSP30
SCHEMBL16012151 0.79 FAAH (0.50) GPR119KDM4EPKMFAAH
SCHEMBL31753585 0.78 GPR119 (0.59) GPR119USP30
SCHEMBL15431347 0.77 IRAK1 (0.56) GPR119IRAK1USP30
SCHEMBL31752813 0.77 GPR119 (0.60) GPR119FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025262297-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 DARK BLUE THERAPEUTICS LTD (GB) 2025-12-26 — — WO disclosed
EP-4667467-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 Dark Blue Therapeutics Ltd (GB) 2025-12-24 — — EP disclosed
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