SCHEMBL31753585

SCHEMBL31753585

CC(C)(C)OC(=O)N1CCC(CCCn2cc(-c3ccc(C#N)c(F)c3)cn2)CC1

nearest known ligand 0.59

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 12/20 0.59
▸ RET P07949 5/20 0.49
▸ JAK2 O60674 1/20 0.44
▸ JAK1 P23458 1/20 0.44
▸ USP30 Q70CQ3 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31752792 0.85 GPR119 (0.49) GPR119USP30
SCHEMBL31752813 0.83 GPR119 (0.60) GPR119RET
SCHEMBL31173852 0.79 GPR119 (0.58) GPR119USP30
SCHEMBL31747263 0.79 GPR119 (0.49) GPR119USP30
SCHEMBL3565646 0.78 GPR119 (0.71) GPR119
SCHEMBL31747481 0.78 GPR119 (0.48) GPR119USP30
SCHEMBL31747452 0.78 GPR119 (0.47) GPR119USP30
SCHEMBL31753579 0.77 GPR119 (0.49) GPR119USP30
SCHEMBL24278903 0.76 KDM1A (0.66) GPR119
SCHEMBL31753322 0.76 GPR119 (0.64) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025262297-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 DARK BLUE THERAPEUTICS LTD (GB) 2025-12-26 — — WO disclosed
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