SCHEMBL31747263

SCHEMBL31747263

CC(C)(C)OC(=O)N1CCC(CCCn2cc(-c3cccc(C(=O)O)c3)cn2)CC1

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 11/20 0.49
▸ KDM4E B2RXH2 1/20 0.48
▸ PKM P14618 1/20 0.48
▸ USP30 Q70CQ3 2/20 0.47
▸ IRAK1 P51617 1/20 0.45
▸ FAAH O00519 2/20 0.44
▸ MEN1 O00255 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ HPGDS O60760 1/20 0.42
▸ TGFBR1 P36897 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31747481 0.92 GPR119 (0.48) GPR119KDM4EPKMUSP30IRAK1
SCHEMBL31747452 0.91 GPR119 (0.47) GPR119KDM4EPKMUSP30IRAK1
SCHEMBL31173852 0.82 GPR119 (0.58) GPR119USP30
SCHEMBL31752792 0.80 GPR119 (0.49) GPR119USP30FAAH
SCHEMBL31753585 0.79 GPR119 (0.59) GPR119USP30
SCHEMBL31753579 0.78 GPR119 (0.49) GPR119USP30FAAH
SCHEMBL15431347 0.78 IRAK1 (0.56) GPR119USP30IRAK1HPGDS
SCHEMBL31747273 0.78 GPR119 (0.50) GPR119KDM4EPKMFAAH
SCHEMBL31752813 0.78 GPR119 (0.60) GPR119FAAH
SCHEMBL31173859 0.77 FAAH (0.50) GPR119KDM4EPKMFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025262297-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 DARK BLUE THERAPEUTICS LTD (GB) 2025-12-26 — — WO disclosed
EP-4667467-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 Dark Blue Therapeutics Ltd (GB) 2025-12-24 — — EP disclosed
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