SCHEMBL6748978

SCHEMBL6748978

CCCC(C(N)=O)=C(CC)CCCN

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.38
KMT2A Q03164 3/20 0.37
GABBR2 O75899 2/20 0.37
GABRR1 P24046 2/20 0.37
GABBR1 Q9UBS5 2/20 0.37
LMNA P02545 2/20 0.37
THRB P10828 2/20 0.37
BLM P54132 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
HDAC3 O15379 2/20 0.37
TSHR P16473 2/20 0.37
HDAC1 Q13547 2/20 0.37
HDAC2 Q92769 2/20 0.37
HDAC8 Q9BY41 2/20 0.37
GABRR3 A8MPY1 1/20 0.37
GABRP O00591 1/20 0.37
GABRD O14764 1/20 0.37
GABRA1 P14867 1/20 0.37
GABRB1 P18505 1/20 0.37
GABRG2 P18507 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6049484 0.86 CYP1A2 (0.42) CYP1A2KMT2AGABBR2GABRR1GABBR1
SCHEMBL28279159 0.83 ALDH1A1 (0.40) CYP1A2KMT2AHDAC3TSHRHDAC1
SCHEMBL317482 0.77 GRIK1 (0.36) CYP1A2PAOX
Ammonia Solution, Strong SCHEMBL27555258 0.74 CES2 (0.39) CYP1A2KMT2AHDAC3TSHRHDAC1
SCHEMBL3357465 0.74 ALDH1A1 (0.40) CYP1A2KMT2AHDAC3TSHRHDAC1
Ammonia Solution, Strong SCHEMBL27608600 0.74 CES2 (0.46) CYP1A2KMT2ATSHRHDAC11ALDH1A1
SCHEMBL28284837 0.73 CES2 (0.47) CYP1A2KMT2AHDAC3TSHRHDAC1
SCHEMBL8743057 0.73 CES1 (0.46) CYP1A2KMT2ATHRBTSHRHDAC11
SCHEMBL797279 0.72 GRIK1 (0.41) CYP1A2KMT2AGABBR2GABRR1GABBR1
SCHEMBL1934407 0.72 PAOX (0.45) CYP1A2KMT2AGABBR2GABRR1GABBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6710024-B2 Washing active preparation BASF AKTIENGESELLSCHAFT (DE) 2004-03-23 US disclosed
US-20030109414-A1 Washing active preparation BASF AKTIENGESELLSCHAFT (DE) 2003-06-12 US disclosed