Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.39 |
| ▸ | ENPEP | Q07075 | 4/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | RRM1 | P23921 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28438892 | 1.00 | OTC (0.39) | OTCENPEPDPP7DDAH1MEN1 | |
| SCHEMBL4317858 | 0.94 | DPP7 (0.38) | OTCENPEPDPP7LTA4HRRM1 | |
| SCHEMBL6191507 | 0.94 | DPP7 (0.38) | OTCENPEPDPP7LTA4HRRM1 | |
| SCHEMBL4317849 | 0.94 | DPP7 (0.38) | OTCENPEPDPP7LTA4HRRM1 | |
| SCHEMBL18983120 | 0.87 | CYP2D6 (0.34) | OTCENPEPLTA4HCYP2D6CYP2C19 | |
| SCHEMBL18983138 | 0.87 | CYP2D6 (0.34) | OTCENPEPLTA4HCYP2D6CYP2C19 | |
| SCHEMBL3180087 | 0.86 | OTC (0.38) | OTCENPEPDPP7DDAH1MEN1 | |
| Hydrochloric Acid SCHEMBL4858131 | 0.85 | LTA4H (0.33) | ENPEPLTA4HCYP2D6CYP2C19 | |
| SCHEMBL30309849 | 0.83 | DPP7 (0.35) | OTCENPEPDPP7DDAH1MEN1 | |
| SCHEMBL20358148 | 0.78 | GNAI3 (0.40) | OTCENPEPDPP7RRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111511740-A | Amide substituted imidazo [4,5-C ] quinoline compounds with branched linking groups for use as immune response modifiers | 3M创新有限公司 | 2020-08-07 | — | — | CN | disclosed |
| US-7655643-B2 | Antibacterial macrocycles with substituted biphenyl | AICURIS GMBH & CO. KG (DE) | 2010-02-02 | — | — | US | disclosed |
| US-20070099885-A1 | Antibacterial macrocycles with substituted biphenyl | AICURIS GMBH & CO. KG (DE) | 2007-05-03 | — | — | US | disclosed |
| US-20050256037-A1 | Antibacterial amide macrocyles | BAYER HEALTHCARE AG (DE) | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099885-A1 | Antibacterial macrocycles with substituted biphenyl | NOD2, AHR, BCL2 | OTC 1790/4885ENPEP 350/4885DPP7 89/4885 |
| US-20050256037-A1 | Antibacterial amide macrocyles | AADAC, PAM, NOD2 | OTC 1050/4885ENPEP 46/4885DPP7 208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.