Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 6/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.35 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.35 |
| ▸ | TXN | P10599 | 1/20 | 0.35 |
| ▸ | CBFB | Q13951 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8174656 | 0.84 | AMY1A (0.36) | ALDH1A1HPGDAMY1AGAAHTT | |
| SCHEMBL1193108 | 0.84 | ALDH1A1 (0.49) | EGLN1ALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL31748325 | 0.81 | CSNK2A1 (0.44) | EGLN1AMY1AGAAHTT | |
| SCHEMBL1193135 | 0.81 | MAPT (0.52) | EGLN1ALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL855939 | 0.78 | MAPT (0.49) | EGLN1IDO1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL2419896 | 0.77 | CACNA1H (0.44) | EGLN1ALDH1A1KDM4ECYP1A2CYP2C9 | |
| SCHEMBL1440759 | 0.77 | ALDH1A1 (0.47) | EGLN1ALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL12844638 | 0.74 | FABP6 (0.43) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2419440 | 0.74 | CACNA1H (0.44) | EGLN1ALDH1A1KDM4ECYP1A2CYP2C9 | |
| SCHEMBL17092653 | 0.73 | EGLN1 (0.55) | EGLN1IDO1HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250388571-A1 | AMP-ACTIVATED PROTEIN KINASE MODULATOR COMPOUNDS AND USES THEREOF | BIOLEXIS THERAPEUTICS INC (US) | 2025-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250388571-A1 | AMP-ACTIVATED PROTEIN KINASE MODULATOR COMPOUNDS AND USES THEREOF | PRKAB2, PRKAB1, PRKAR2B | EGLN1 3554/4885IDO1 4856/4885ALDH1A1 4339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.