Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31750777 | 0.84 | RXRA (0.36) | DGAT2ALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL31750490 | 0.82 | RXRA (0.35) | DGAT2ALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL31751088 | 0.81 | RXRA (0.35) | DGAT2ALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL31750477 | 0.80 | KDM4E (0.36) | DGAT2ALDH1A1KDM4EHSD17B10RXRA | |
| SCHEMBL31393226 | 0.75 | DGAT2 (0.36) | DGAT2RXRARXRBRXRGCYP4F2 | |
| SCHEMBL31750142 | 0.75 | RXRA (0.44) | DGAT2ALDH1A1KDM4ETSHRRXRA | |
| SCHEMBL31585717 | 0.72 | CYP4F2 (0.37) | DGAT2RXRARXRBRXRGGAA | |
| SCHEMBL31750483 | 0.71 | RXRA (0.33) | DGAT2ALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL31750482 | 0.71 | RXRA (0.42) | ALDH1A1KDM4ETSHRRXRARXRB | |
| SCHEMBL16052480 | 0.71 | YTHDC1 (0.35) | DGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025262250-A1 | GUANFACINE DERIVATIVES AND THEIR USES | NEGIO THERAPEUTICS (BE) | 2025-12-26 | — | — | WO | disclosed |