Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B2 | P80365 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31752274 | 0.95 | SPHK1 (0.38) | HSD11B2SPHK1BRD4EPHA2PIK3CD | |
| SCHEMBL31751249 | 0.76 | HSD11B2 (0.35) | HSD11B2SPHK1BRD4 | |
| SCHEMBL24613291 | 0.74 | SPHK1 (0.43) | HSD11B2SPHK1BRD4 | |
| SCHEMBL26964224 | 0.74 | SPHK1 (0.43) | HSD11B2SPHK1BRD4 | |
| SCHEMBL15209132 | 0.73 | SPHK1 (0.48) | HSD11B2SPHK1BRD4 | |
| SCHEMBL15209134 | 0.73 | SPHK1 (0.48) | HSD11B2SPHK1BRD4 | |
| SCHEMBL8945204 | 0.73 | HTR2C (0.38) | HSD11B2SPHK1BRD4 | |
| SCHEMBL8945093 | 0.72 | FAAH (0.41) | HSD11B2SPHK1BRD4EPHA2 | |
| SCHEMBL19357528 | 0.72 | SPHK1 (0.44) | HSD11B2SPHK1BRD4 | |
| SCHEMBL3612721 | 0.72 | SPHK1 (0.44) | HSD11B2SPHK1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025264954-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2025-12-26 | — | — | WO | disclosed |