Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 3/20 | 0.35 |
| ▸ | KDM1A | O60341 | 4/20 | 0.34 |
| ▸ | GAK | O14976 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22324231 | 0.89 | PDGFRB (0.47) | PDGFRBPDGFRAEGFRPDE10AALDH1A1 | |
| SCHEMBL16431930 | 0.86 | PDGFRB (0.59) | PDGFRBPDGFRAEGFRPDE10AALDH1A1 | |
| SCHEMBL22323962 | 0.84 | PDGFRB (0.47) | PDGFRBPDGFRAEGFRPDE10AALDH1A1 | |
| SCHEMBL29447097 | 0.84 | PDGFRB (0.47) | PDGFRBPDGFRAEGFRPDE10AALDH1A1 | |
| SCHEMBL28694507 | 0.83 | PDGFRB (0.41) | PDGFRBPDGFRAEGFRPDE10AALOX15 | |
| SCHEMBL21645897 | 0.81 | PDGFRB (0.59) | PDGFRBPDGFRAEGFRPDE10AALDH1A1 | |
| SCHEMBL28102697 | 0.79 | PDGFRB (0.67) | PDGFRBPDGFRAEGFRKDM1AGAK | |
| SCHEMBL262387 | 0.74 | LPL (0.37) | KDM1AALDH1A1HTTGAANPSR1 | |
| SCHEMBL29534512 | 0.74 | LPL (0.37) | KDM1AALDH1A1HTTGAANPSR1 | |
| SCHEMBL19491485 | 0.73 | DGAT1 (0.33) | EGFRKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12509460-B2 | Methods and compositions for modulating splicing | SKYHAWK THERAPEUTICS, INC. (US) | 2025-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12509460-B2 | Methods and compositions for modulating splicing | SF3B1, RTCB, RBM17 | PDGFRB 3552/4885PDGFRA 4055/4885EGFR 4466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.