Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 9/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ESRRA | P11474 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30808866 | 0.87 | TP53 (0.55) | TP53ALOX12HTTMAPTPOLB | |
| SCHEMBL31755892 | 0.82 | NR1I2 (0.42) | TP53HTTMAPTLMNAPOLB | |
| SCHEMBL3491869 | 0.82 | HTT (0.58) | TP53ALOX12HTTNFE2L2KEAP1 | |
| SCHEMBL31755988 | 0.76 | DCTPP1 (0.51) | TP53ALOX12HTTNFE2L2KEAP1 | |
| SCHEMBL31755652 | 0.75 | HTT (0.49) | TP53ALOX12HTTNFE2L2KEAP1 | |
| SCHEMBL31755714 | 0.73 | CA1 (0.49) | TP53ALOX12HTTNFE2L2KEAP1 | |
| SCHEMBL31756152 | 0.72 | CA1 (0.37) | HTTNFE2L2KEAP1POLBGAA | |
| SCHEMBL30808851 | 0.71 | HTT (0.41) | TP53ALOX12HTTNFE2L2KEAP1 | |
| SCHEMBL30808870 | 0.70 | HTT (0.50) | TP53ALOX12HTTNFE2L2KEAP1 | |
| SCHEMBL3463266 | 0.69 | HTT (0.41) | HTTNFE2L2KEAP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260001871-A1 | TRIAZOLE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR D | ESCIENT PHARMACEUTICALS INC (US) | 2026-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260001871-A1 | TRIAZOLE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR D | MRGPRX2, MC2R, MRGPRX1 | TP53 4481/4885ALOX12 4328/4885HTT 2816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.