Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31756039 | 0.84 | CRACR2A (0.40) | HTTKMT2AMAPTTP53LMNA | |
| SCHEMBL31755653 | 0.82 | TP53 (0.43) | HTTMAPTTP53LMNASMN1; SMN2 | |
| SCHEMBL30808866 | 0.79 | TP53 (0.55) | HTTKMT2AMAPTTP53ALDH1A1 | |
| SCHEMBL31755979 | 0.78 | MET (0.47) | NR1I2KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL31755932 | 0.77 | CRACR2A (0.41) | HTTKMT2AMAPTLMNARIPK1 | |
| SCHEMBL31756155 | 0.75 | HIF1A (0.44) | HTTMAPTTP53LMNARIPK1 | |
| SCHEMBL31756327 | 0.74 | PRKCI (0.46) | NR1I2HTTKMT2AMAPTTP53 | |
| SCHEMBL31755629 | 0.72 | CRACR2A (0.37) | NR1I2KMT2AMAPTTP53LMNA | |
| SCHEMBL31755912 | 0.71 | MAPT (0.48) | KMT2AMAPTTP53RIPK1ALDH1A1 | |
| SCHEMBL31755995 | 0.71 | CRACR2A (0.41) | HTTALDH1A1RAB9ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260001871-A1 | TRIAZOLE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR D | ESCIENT PHARMACEUTICALS INC (US) | 2026-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260001871-A1 | TRIAZOLE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR D | MRGPRX2, MC2R, MRGPRX1 | NR1I2 352/4885HTT 2816/4885KMT2A 4128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.