SCHEMBL3175936

SCHEMBL3175936

O=C(Cl)C1CCC(C(=O)Cl)C(C(=O)Cl)C1

nearest known ligand 0.30

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.30
CHRNB4 P30926 1/20 0.30
CHRNA3 P32297 1/20 0.30
CHRNA7 P36544 1/20 0.30
CHRNA4 P43681 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3175923 1.00 CHRNB2 (0.30) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL6362850 1.00 CHRNB2 (0.30) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL3175928 1.00 CHRNB2 (0.30) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL3795815 0.85 GABRR1 (0.30)
SCHEMBL2154406 0.82 ACE (0.36) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL2266700 0.82 GABRR1 (0.35)
SCHEMBL17237823 0.82 GABRR1 (0.35)
SCHEMBL7271372 0.82 GABRR1 (0.35)
SCHEMBL4279 0.78
SCHEMBL1506461 0.78 CHRNB2 (0.36) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109796591-B Polyimide precursor, polyimide nano composite film and preparation method thereof 武汉柔显科技股份有限公司 2021-04-27 CN disclosed
US-10654002-B2 Thin film composite forward osmosis membranes with performance enhancing layers INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2020-05-19 US disclosed
US-10384172-B2 Composite membrane with multi-layered active layer INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2019-08-20 US disclosed
US-10293308-B2 Antifouling and antimicrobial coatings for thin film composite membranes INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2019-05-21 US disclosed
US-20190015789-A1 ANTIFOULING AND ANTIMICROBIAL COATINGS FOR THIN FILM COMPOSITE MEMBRANES INTERNATIONAL BUSINESS MACHINES CORPORATION 2019-01-17 US disclosed
US-10005042-B2 Thin film composite forward osmosis membranes with performance enhancing layers INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-06-26 US disclosed
US-20170144113-A1 COMPOSITE MEMBRANE WITH MULTI-LAYERED ACTIVE LAYER INTERNATIONAL BUSINESS MACHINES CORPORATION 2017-05-25 US disclosed
US-9579608-B2 Composite membranes and methods of preparation thereof GLOBALFOUNDRIES INC. (KY) 2017-02-28 US disclosed
US-9561474-B2 Composite membrane with multi-layered active layer INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2017-02-07 US disclosed
US-20170001151-A1 ANTIFOULING AND ANTIMICROBIAL COATINGS FOR THIN FILM COMPOSITE MEMBRANES INTERNATIONAL BUSINESS MACHINES CORPORATION 2017-01-05 US disclosed
US-8895104-B2 Thin film composite membranes embedded with molecular cage compounds INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-11-25 US disclosed
US-8857629-B2 Composite membrane with multi-layered active layer INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-10-14 US disclosed
US-8754139-B2 Polyamide membranes with fluoroalcohol functionality INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-06-17 US disclosed
US-8754139-B2 Polyamide membranes with fluoroalcohol functionality INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-06-17 US disclosed
WO-2013006288-A1 THIN FILM COMPOSITE MEMBRANES EMBEDDED WITH MOLECULAR CAGE COMPOUNDS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-01-10 WO disclosed
US-20130001153-A1 THIN FILM COMPOSITE MEMBRANES EMBEDDED WITH MOLECULAR CAGE COMPOUNDS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-01-03 US disclosed
US-20100216899-A1 POLYAMIDE MEMBRANES WITH FLUOROALCOHOL FUNCTIONALITY INTERNATIONAL BUSINESS MACHINES CORPORATION 2010-08-26 US disclosed
US-20100216967-A1 INTERFACIAL POLYMERIZATION METHODS FOR MAKING FLUOROALCOHOL-CONTAINING POLYAMIDES INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-08-26 US disclosed
US-7645805-B2 Gelling agents APPLIED NANOSYSTEMS, B.V. (NL) 2010-01-12 US disclosed
US-20050250857-A1 Gelling agents NANO FIBER MATRICES B.V. (NL) 2005-11-10 US disclosed