Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 6/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.53 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.53 |
| ▸ | APP | P05067 | 5/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SPR | P35270 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9314481 | 0.78 | AKR1C1 (0.45) | AKR1C3AKR1C2AKR1C1APPCYP2C19 | |
| SCHEMBL31759338 | 0.77 | AKR1C3 (0.49) | AKR1C3AKR1C2AKR1C1APPCYP2C19 | |
| SCHEMBL28083408 | 0.77 | AKR1C3 (0.50) | AKR1C3AKR1C2AKR1C1APPCYP2C19 | |
| SCHEMBL12303757 | 0.77 | CPS1 (0.40) | AKR1C3AKR1C2AKR1C1APPCYP2C19 | |
| SCHEMBL348608 | 0.77 | AKR1C3 (0.49) | AKR1C3AKR1C2AKR1C1APPCYP2C19 | |
| SCHEMBL20242022 | 0.74 | AKR1C3 (0.50) | AKR1C3AKR1C2AKR1C1APPCYP2C19 | |
| SCHEMBL20242254 | 0.74 | HDAC4 (0.60) | AKR1C3AKR1C2AKR1C1APPCYP2C19 | |
| SCHEMBL14973733 | 0.74 | AKR1C3 (0.43) | AKR1C3AKR1C2AKR1C1APPCYP2C19 | |
| SCHEMBL20242053 | 0.74 | AKR1C3 (0.45) | AKR1C3AKR1C2AKR1C1APPCYP2C19 | |
| SCHEMBL16585418 | 0.74 | AKR1C1 (0.57) | AKR1C3AKR1C2AKR1C1APPCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260007684-A1 | AMIDE DERIVATIVES FOR INHIBITING NLRP3 AND USES THEREOF | VENTUS THERAPEUTICS U S INC (US) | 2026-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260007684-A1 | AMIDE DERIVATIVES FOR INHIBITING NLRP3 AND USES THEREOF | NOD1, NLRP3, NOD2 | AKR1C3 314/4885AKR1C2 761/4885AKR1C1 834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.