Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1679940 | 0.80 | — | — | |
| SCHEMBL1524596 | 0.75 | ELANE (0.33) | ELANELMNAHSD17B10MEN1KMT2A | |
| SCHEMBL3175570 | 0.74 | — | — | |
| SCHEMBL24075527 | 0.70 | CTSK (0.32) | CYP4F2CYP4A11 | |
| SCHEMBL24521405 | 0.69 | CES2 (0.31) | ELANEMEN1KMT2ATDP1 | |
| SCHEMBL11684085 | 0.68 | ELANE (0.30) | ELANE | |
| SCHEMBL26130133 | 0.65 | ELANE (0.43) | ELANELMNAHSD17B10MEN1KMT2A | |
| SCHEMBL14244834 | 0.65 | ACLY (0.44) | HSD17B10MEN1KMT2ATDP1 | |
| SCHEMBL8420497 | 0.65 | ACLY (0.44) | HSD17B10MEN1KMT2ATDP1 | |
| SCHEMBL7758102 | 0.64 | LMNA (0.38) | ELANELMNAHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662937-B2 | Polymerizable dye and ophthalmic lens containing the same | MENICON CO., LTD. (JP) | 2010-02-16 | — | — | US | disclosed |
| US-20090082553-A1 | Novel Polymerizable Dye and Ophthalmic Lens Containing the Same | MENICON CO., LTD. (JP) | 2009-03-26 | — | — | US | disclosed |