Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 10/20 | 0.65 |
| ▸ | HTR2B | P41595 | 7/20 | 0.65 |
| ▸ | HTR2A | P28223 | 9/20 | 0.53 |
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 3/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | INPPL1 | O15357 | 2/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | INPP5A | Q14642 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30681655 | 1.00 | HTR2C (0.65) | HTR2CHTR2BHTR2AHTR1ATAAR1 | |
| SCHEMBL31188169 | 0.87 | HTR2C (0.59) | HTR2CHTR2BHTR2AHTR1ATAAR1 | |
| SCHEMBL3176621 | 0.87 | HTR2C (0.59) | HTR2CHTR2BHTR2AHTR1ATAAR1 | |
| SCHEMBL3804057 | 0.83 | HTR1A (0.46) | HTR2CHTR2BHTR2AHTR1ATAAR1 | |
| SCHEMBL3804505 | 0.81 | HTR2C (0.41) | HTR2CHTR2BHTR2AHTR1ATAAR1 | |
| SCHEMBL13592771 | 0.79 | HTR2C (0.49) | HTR2CHTR2BHTR2AHTR1ATAAR1 | |
| SCHEMBL30356554 | 0.79 | HTR2C (1.00) | HTR2CHTR2BHTR2AHTR1AHTR6 | |
| SCHEMBL29405683 | 0.79 | HTR2C (1.00) | HTR2CHTR2BHTR2AHTR1AHTR6 | |
| SCHEMBL3792128 | 0.79 | HTR2C (0.40) | HTR2CHTR2BHTR2AHTR1ATAAR1 | |
| Hydrochloric Acid SCHEMBL4394176 | 0.78 | HTR2C (0.48) | HTR2CHTR2BHTR2AHTR1ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7655691-B2 | Indole compounds useful as serotonin selective agents | ORGANIX, INC. | 2010-02-02 | — | — | US | claimed |
| US-8071786-B2 | Indole compounds useful as serotonin selective agents | GALENEA CORP. (US) | 2011-12-06 | — | — | US | disclosed |
| US-20100137616-A1 | INDOLE COMPOUNDS USEFUL AS SEROTONIN SELECTIVE AGENTS | SARD HOWARD P | 2010-06-03 | — | — | US | disclosed |
| US-7655691-B2 | Indole compounds useful as serotonin selective agents | ORGANIX, INC. | 2010-02-02 | — | — | US | disclosed |
| US-7655691-B2 | Indole compounds useful as serotonin selective agents | ORGANIX, INC. | 2010-02-02 | — | — | US | disclosed |
| US-7655691-B2 | Indole compounds useful as serotonin selective agents | ORGANIX, INC. | 2010-02-02 | — | — | US | disclosed |
| US-20060100266-A1 | Indole compounds useful as serotonin selective agents | ORGANIX, INC. (US) | 2006-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137616-A1 | INDOLE COMPOUNDS USEFUL AS SEROTONIN SELECTIVE AGENTS | TPH1, TPH2, AANAT | HTR2C 15/4885HTR2B 16/4885HTR2A 11/4885 |
| US-20060100266-A1 | Indole compounds useful as serotonin selective agents | TPH1, TPH2, AANAT | HTR2C 15/4885HTR2B 16/4885HTR2A 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.