SCHEMBL3177799

SCHEMBL3177799

CC(C)(C)OC(=O)N(CCOS(C)(=O)=O)C(c1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.37
PTGIR P43119 1/20 0.37
AKT1 P31749 2/20 0.36
MMP13 P45452 1/20 0.35
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA7 P43166 1/20 0.34
CA14 Q9ULX7 1/20 0.34
CTSS P25774 1/20 0.34
CTSK P43235 1/20 0.34
F2 P00734 2/20 0.34
NPSR1 Q6W5P4 1/20 0.34
CCR5 P51681 1/20 0.34
LMNA P02545 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3162396 0.81 PTGIR (0.41) L3MBTL1PTGIRAKT1CTSSCTSK
SCHEMBL3183520 0.79 L3MBTL1 (0.37) L3MBTL1PTGIRAKT1CTSSCTSK
SCHEMBL28643624 0.78 F2 (0.52) L3MBTL1AKT1CA12CA1CA7
SCHEMBL26482099 0.76 L3MBTL1 (0.43) L3MBTL1PTGIRAKT1CTSSCTSK
SCHEMBL7650960 0.74 RXRA (0.35) L3MBTL1CA12CA1LMNA
SCHEMBL2797220 0.72 HDAC3 (0.47) L3MBTL1AKT1CA12CA1CA7
SCHEMBL31569335 0.72 SSTR4 (0.31)
SCHEMBL3174927 0.72 CA14 (0.42) L3MBTL1CA12CA1CA7CA14
SCHEMBL8362264 0.72 MMP13 (0.41) AKT1MMP13CA12CA1CA7
SCHEMBL7646277 0.72 SLC7A5 (0.38) CA12CA1CA14F2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8715635-B2 Frictionless molecular rotary motors TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2014-05-06 US disclosed
US-20100016610-A1 FRICTIONLESS MOLECULAR ROTARY MOTORS TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) 2010-01-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100016610-A1 FRICTIONLESS MOLECULAR ROTARY MOTORS DYNLL2, ATXN2L, DYNLL1 L3MBTL1 2840/4885PTGIR 3833/4885AKT1 1407/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.