Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 2/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 4/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 2/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7650960 | 0.92 | RXRA (0.35) | SLC7A5CASRCA12CA1CA2 | |
| SCHEMBL7648073 | 0.85 | SLC7A5 (0.42) | SLC7A5CASRSTAT3TP53BP1ACHE | |
| SCHEMBL7646150 | 0.84 | SLC7A5 (0.41) | SLC7A5CASRSTAT3TP53BP1ACHE | |
| SCHEMBL7646280 | 0.77 | SLC7A5 (0.43) | SLC7A5CASRSTAT3 | |
| SCHEMBL7647701 | 0.76 | ANPEP (0.38) | SLC7A5CASRTP53BP1 | |
| SCHEMBL14415230 | 0.74 | SLC7A5 (0.51) | SLC7A5STAT3F2CA12CA1 | |
| SCHEMBL7021584 | 0.73 | SLC7A5 (0.46) | SLC7A5CASRSTAT3F2CA12 | |
| SCHEMBL7021578 | 0.73 | SLC7A5 (0.46) | SLC7A5CASRSTAT3F2CA12 | |
| SCHEMBL3177799 | 0.72 | L3MBTL1 (0.37) | F2CA12CA1CA14CYP1A2 | |
| SCHEMBL7498901 | 0.71 | SLC7A5 (0.53) | SLC7A5STAT3F2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100871-A1 | NEW COMPOUNDS USEFUL IN REFLUX DISEASE | ASTRAZENECA AB (SE) | 2002-12-19 | — | — | WO | claimed |
| WO-2002100871-A1 | NEW COMPOUNDS USEFUL IN REFLUX DISEASE | ASTRAZENECA AB (SE) | 2002-12-19 | — | — | WO | disclosed |