SCHEMBL317794

SCHEMBL317794

COC(O)(OC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
CES1 P23141 1/20 0.51
LMNA P02545 2/20 0.45
F2 P00734 1/20 0.45
TDP1 Q9NUW8 3/20 0.44
ALDH1A1 P00352 3/20 0.44
HSD17B10 Q99714 1/20 0.44
MAPT P10636 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
SRC P12931 1/20 0.43
CYP2C19 P33261 2/20 0.43
KCNN4 O15554 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
HIF1A Q16665 2/20 0.42
MAPK1 P28482 1/20 0.42
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL784070 0.80 TSHR (0.53) TSHRCES1LMNAF2TDP1
SCHEMBL3396959 0.79 LMNA (0.54) TSHRCES1LMNAF2TDP1
SCHEMBL319709 0.78 CES1 (0.47) TSHRCES1ALDH1A1MAPTSRC
SCHEMBL4737765 0.77 LMNA (0.52) TSHRCES1LMNAF2TDP1
SCHEMBL783600 0.77 TSHR (0.59) TSHRCES1LMNAF2TDP1
SCHEMBL784820 0.76 TSHR (0.57) TSHRCES1LMNAF2TDP1
SCHEMBL22924627 0.76 TSHR (0.57) TSHRCES1LMNAF2TDP1
SCHEMBL8945819 0.75 TSHR (0.57) TSHRLMNAF2TDP1ALDH1A1
SCHEMBL11146170 0.75 LMNA (0.54) TSHRCES1LMNAF2TDP1
SCHEMBL4733273 0.75 LMNA (0.46) TSHRCES1LMNATDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008060844-A1 POLYMERIZATION INHIBITOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE ALBEMARLE CORPORATION (US) 2008-05-22 WO claimed
US-20240242701-A1 SOUND INSULATION SHEET AND SOUND INSULATION STRUCTURE MITSUBISHI CHEMICAL CORPORATION (JP) 2024-07-18 US disclosed
EP-4370611-A1 COATING COMPOSITION Jotun A/S (NO) 2024-05-22 EP disclosed
EP-3378887-B1 FIBER-REINFORCED-PLASTIC MOLDED ARTICLE AND PRODUCTION PROCESS THEREFOR JAPAN U PICA CO LTD (JP) 2024-05-08 EP disclosed
US-11931990-B2 Composition for sound insulating sheet member, sound insulating sheet member, and sound insulating structure body MITSUBISHI CHEMICAL CORPORATION (JP) 2024-03-19 US disclosed
US-20240042742-A1 COMPOSITION FOR SOUND INSULATING SHEET MEMBER, SOUND INSULATING SHEET MEMBER, AND SOUND INSULATING STRUCTURE BODY MITSUBISHI CHEMICAL CORPORATION (JP) 2024-02-08 US disclosed
EP-4310112-A1 RESIN COMPOSITION, PREPREG, AND FIBER-REINFORCED PLASTIC Mitsubishi Chemical Corporation (JP) 2024-01-24 EP disclosed
US-20230383077-A1 RESIN COMPOSITION, PREPREG, AND FIBER-REINFORCED PLASTIC MITSUBISHI CHEMICAL CORPORATION (JP) 2023-11-30 US disclosed
WO-2023209855-A1 ADDITION TYPE POLYMER AND SILICONE HYDROGEL LENS MATERIAL 株式会社メニコン 2023-11-02 WO disclosed
US-20230250631-A1 SOUND-INSULATING STRUCTURAL BODY MITSUBISHI CHEMICAL CORPORATION (JP) 2023-08-10 US disclosed
US-20070128365-A1 RADIATION-CURABLE, ELECTRICALLY CONDUCTIVE COATIING MIXTURE HENKEL AG & CO. KGAA (DE) 2007-06-07 US disclosed
US-7160488-B2 Method of manufacturing intraocular lenses and intraocular lenses manufactured by the method NIDEK CO., LTD. (JP) 2007-01-09 US disclosed
EP-1393694-B1 Method of manufacturing intraocular lenses NIDEK KK (JP) 2006-11-02 EP disclosed
EP-1369710-B1 Method of manufacturing intraocular lenses and intraocular lenses manufactured by the method NIDEK KK (JP) 2006-07-26 EP disclosed
US-20040041289-A1 Method of manufacturing intraocular lenses and intraocular lenses manufactured by the method NIDEK CO., LTD. (JP) 2004-03-04 US disclosed
EP-1393694-A1 Method of manufacturing intraocular lenses and intraocular lenses manufactured by the method NIDEK CO., LTD (JP) 2004-03-03 EP disclosed
EP-1369710-A2 Method of manufacturing intraocular lenses and intraocular lenses manufactured by the method NIDEK CO., LTD (JP) 2003-12-10 EP disclosed
EP-1030194-B1 Material for a soft intraocular lens MENICON CO LTD (JP) 2002-12-04 EP disclosed
US-6277940-B1 TRANSPARENCY AND FLEXIBILITY, REFRACTIVE INDEX, CAN BE INSERTED FROM A SMALL INCISION MENICON CO. LTD (JP) 2001-08-21 US disclosed
EP-1030194-A1 Material for a soft intraocular lens Menicon Co., Ltd. (JP) 2000-08-23 EP disclosed