Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10609830 | 0.78 | TSHR (0.44) | LMNATSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL1470605 | 0.78 | TSHR (0.44) | LMNATSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL10718160 | 0.77 | TSHR (0.40) | LMNATSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL13754160 | 0.76 | CES1 (0.55) | LMNATSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL9303826 | 0.76 | CES1 (0.55) | LMNATSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL1259271 | 0.76 | SOAT2 (0.45) | ALDH1A1 | |
| SCHEMBL1259268 | 0.76 | SOAT2 (0.45) | ALDH1A1 | |
| SCHEMBL9068153 | 0.76 | TSHR (0.47) | LMNATSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL246510 | 0.75 | TDP1 (0.79) | LMNATSHRALDH1A1TDP1TP53 | |
| SCHEMBL317794 | 0.75 | TSHR (0.52) | LMNATSHRALDH1A1TDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008060844-A1 | POLYMERIZATION INHIBITOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE | ALBEMARLE CORPORATION (US) | 2008-05-22 | — | — | WO | disclosed |