SCHEMBL3396959

SCHEMBL3396959

O=C(OC(c1ccccc1)(c1ccccc1)c1ccccc1)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.54
F2 P00734 1/20 0.54
TSHR P16473 4/20 0.50
HIF1A Q16665 2/20 0.48
MAPK1 P28482 1/20 0.48
TDP1 Q9NUW8 4/20 0.47
ALDH1A1 P00352 4/20 0.47
HSD17B10 Q99714 1/20 0.47
MAPT P10636 3/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CES1 P23141 3/20 0.46
TP53 P04637 1/20 0.45
CYP2C19 P33261 2/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2D6 P10635 1/20 0.45
KMT2A Q03164 3/20 0.44
POLB P06746 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A3 Q01959 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27480443 0.85 AKR1C3 (0.47) LMNAF2TSHRTDP1HSD17B10
SCHEMBL28249448 0.84 CA12 (0.52) LMNAMAPK1ALDH1A1MAPTKMT2A
SCHEMBL11146170 0.83 LMNA (0.54) LMNAF2TSHRHIF1AMAPK1
SCHEMBL8582147 0.82 PTPN1 (0.39) LMNAF2TSHRHIF1AMAPK1
SCHEMBL4737765 0.81 LMNA (0.52) LMNAF2TSHRHIF1AMAPK1
SCHEMBL8746377 0.79 KCNN4 (0.45) LMNAF2TSHRHIF1AMAPK1
SCHEMBL14935466 0.79 KCNN4 (0.45) LMNAF2TSHRHIF1AMAPK1
SCHEMBL2442870 0.79 KCNN4 (0.45) LMNAF2TSHRHIF1AMAPK1
SCHEMBL28706308 0.79 LMNA (0.61) LMNAF2TSHRHIF1AMAPK1
SCHEMBL317794 0.79 TSHR (0.52) LMNAF2TSHRHIF1AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116284216-A Aromatic dipeptide functionalized sulfhydryl compound and preparation method and application thereof 华能武汉发电有限责任公司 2023-06-23 CN claimed
EP-1572752-B1 POLYMERIZATION PROCESSES EXXONMOBIL CHEM PATENTS INC (US) 2014-08-13 EP claimed
EP-1578806-B1 POLYMERIZATION PROCESSES EXXONMOBIL CHEM PATENTS INC (US) 2013-05-22 EP claimed
EP-1572753-B1 POLYMERIZATION PROCESSES EXXONMOBIL CHEM PATENTS INC (US) 2012-06-13 EP claimed
EP-1761574-B1 POLYMERIZATION PROCESS USING HYDROFLUOROCARBONS EXXONMOBIL CHEM PATENTS INC (US) 2012-06-13 EP claimed
EP-1572751-B1 POLYMERIZATION PROCESSES EXXONMOBIL CHEM PATENTS INC (US) 2010-06-23 EP claimed
EP-0648220-A1 DEUTERATED NUCLEOSIDES CHATTOPADHYAYA, Jyoti (SE) 1995-04-19 EP claimed
CN-118355117-A Oligonucleotide compositions and methods thereof 波涛生命科学有限公司 2024-07-16 CN disclosed
CN-118139629-A Compositions and methods for editing MECP2 transcripts 波涛生命科学有限公司 2024-06-04 CN disclosed
CN-118139977-A Double-stranded oligonucleotide compositions and methods relating thereto 波涛生命科学有限公司 2024-06-04 CN disclosed
CN-117965536-A Oligonucleotide compositions and methods thereof 波涛生命科学有限公司 2024-05-03 CN disclosed
CN-117794560-A Stapled peptides and methods thereof 弗格制药有限公司 2024-03-29 CN disclosed
CN-117412761-A Antibody drug conjugates for delivery of cytotoxic agents using MATE technology 拜奥海芬治疗学有限公司 2024-01-16 CN disclosed
CN-1264705-A Method for preparing substituted benzodihydropyran derivative BASF AG (DE) 2000-08-30 CN disclosed
WO-2000028063-A1 CATALYTIC ANTIBODIES AND METHOD FOR PRODUCING CHROMANES BY CYCLIZATION WITH SAID ANTIBODIES BASF AKTIENGESELLSCHAFT (DE) 2000-05-18 WO disclosed
WO-2000028330-A1 METHOD FOR SELECTING CATALYTIC ANTIBODIES BASF AKTIENGESELLSCHAFT (DE) 2000-05-18 WO disclosed
WO-2000027884-A1 ANTIBODIES, MINI-ANTIBODIES OR ANTIBODY FRAGMENTS BINDING TO VITAMIN E AND THE USE THEREOF BASF AKTIENGESELLSCHAFT (DE) 2000-05-18 WO disclosed
CN-1249306-A Process for preparing benzodihydropyranol deriv. BASF AG (DE) 2000-04-05 CN disclosed
CN-1111249-A TTTr as protective group in nucleotide synthesis CIBA GEIGY AG (CH) 1995-11-08 CN disclosed
US-4346187-A AND ORGANIC BROMINE COMPOUND BORG-WARNER CHEMICALS, INC. (US) 1982-08-24 US disclosed