Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HPN | P05981 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3176272 | 0.84 | GABRA1 (0.34) | GABRA1GABRB2POLBHSP90AA1ALOX15 | |
| SCHEMBL3178010 | 0.78 | GABRA1 (0.40) | GABRA1GABRB2POLBHSP90AA1ALOX15 | |
| SCHEMBL14640959 | 0.76 | GABRA1 (0.39) | GABRA1GABRB2POLBHSP90AA1ALOX15 | |
| SCHEMBL3175394 | 0.74 | CA2 (0.46) | GABRA1GABRB2ALDH1A1TDP1TSHR | |
| SCHEMBL24344713 | 0.71 | POLB (0.41) | GABRA1GABRB2POLBHSP90AA1ALOX15 | |
| SCHEMBL9173094 | 0.71 | ALDH1A1 (0.46) | GABRA1GABRB2POLBHSP90AA1ALOX15 | |
| SCHEMBL139483 | 0.70 | GABRA1 (0.42) | GABRA1GABRB2POLBHSP90AA1ALOX15 | |
| SCHEMBL3175072 | 0.70 | GABRA1 (0.33) | GABRA1GABRB2POLBHSP90AA1ALOX15 | |
| SCHEMBL11357994 | 0.67 | POLB (0.46) | GABRA1GABRB2POLBHSP90AA1ALOX15 | |
| SCHEMBL7136246 | 0.67 | GABRA1 (0.43) | GABRA1GABRB2POLBHSP90AA1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8076430-B2 | Living radical polymerization promoter | OTSUKA CHEMICAL CO., LTD. (JP) | 2011-12-13 | — | — | US | disclosed |
| US-20100022728-A1 | LIVING RADICAL POLYMERIZATION PROMOTER | OTSUKA CHEMICAL CO., LTD. (JP) | 2010-01-28 | — | — | US | disclosed |
| EP-2133357-A1 | LIVING RADICAL POLYMERIZATION PROMOTER | Otsuka Chemical Holdings Co., Ltd. (JP) | 2009-12-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022728-A1 | LIVING RADICAL POLYMERIZATION PROMOTER | DNMT1, CYP1B1, DNMT3B | GABRA1 3794/4885GABRB2 2846/4885POLB 232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.