SCHEMBL3178593

SCHEMBL3178593

CCCOc1cc(N(CC)CC)ccc1C1(c2c(C)n(CC)c3ccccc23)OC(=O)c2cccnc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
LMNA P02545 3/20 0.32
HTT P42858 2/20 0.32
MAPT P10636 3/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
HCRTR1 O43613 1/20 0.31
TSHR P16473 1/20 0.31
CASP1 P29466 1/20 0.31
CASP7 P55210 1/20 0.31
HBB P68871 1/20 0.31
KMT2A Q03164 1/20 0.31
ATM Q13315 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TLR9 Q9NR96 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3227135 0.96 ALDH1A1 (0.31) ALDH1A1SMN1; SMN2
SCHEMBL9467342 0.96 LMNA (0.32) ALDH1A1SMN1; SMN2LMNAHTTMAPT
SCHEMBL20987295 0.96 HTT (0.33) ALDH1A1SMN1; SMN2LMNAHTTMAPT
SCHEMBL10661081 0.95 PLA2G2A (0.32) ALDH1A1SMN1; SMN2LMNAHTTMEN1
SCHEMBL30009305 0.95 PLA2G2A (0.32) ALDH1A1SMN1; SMN2LMNAHTTMEN1
SCHEMBL10596820 0.95 PLA2G2A (0.32) ALDH1A1SMN1; SMN2LMNAHTTMEN1
SCHEMBL891165 0.95 PLA2G2A (0.32) ALDH1A1SMN1; SMN2LMNAHTTMEN1
SCHEMBL29496955 0.95 PLA2G2A (0.32) ALDH1A1SMN1; SMN2LMNAHTTMEN1
SCHEMBL29383067 0.94 SMN1; SMN2 (0.35) ALDH1A1SMN1; SMN2LMNAHTTMAPT
SCHEMBL30122739 0.94 SMN1; SMN2 (0.35) ALDH1A1SMN1; SMN2LMNAHTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9834022-B2 Thermal recording material MITSUBISHI PAPER MILLS LIMITED (JP) 2017-12-05 US disclosed
EP-3031611-B1 THERMAL RECORDING MATERIAL MITSUBISHI PAPER MILLS LTD (JP) 2017-09-27 EP disclosed
US-20160332469-A1 THERMAL RECORDING MATERIAL MITSUBISHI PAPER MILLS LIMITED (JP) 2016-11-17 US disclosed
EP-3031611-A1 THERMAL RECORDING MATERIAL Mitsubishi Paper Mills Limited (JP) 2016-06-15 EP disclosed
EP-2096149-B1 INK FOR SCRATCH COLORING AND SHEET WITH INVISIBLE INFORMATION PRINTED MITSUBISHI PAPER MILLS LTD (JP) 2014-10-22 EP disclosed
US-8283285-B2 Scratch color-developable ink and invisible information printed sheet MITSUBISHI PAPER MILLS LIMITED (JP) 2012-10-09 US disclosed
US-20100021702-A1 SCRATCH COLOR-DEVELOPABLE INK AND INVISIBLE INFORMATION PRINTED SHEET MITSUBISHI PAPER INK MFG. CO., LTD. (JP) 2010-01-28 US disclosed
EP-2096149-A1 INK FOR SCRATCH COLORING AND SHEET WITH INVISIBLE INFORMATION PRINTED Mitsubishi Paper Mills Limited (JP) 2009-09-02 EP disclosed
US-6960553-B2 Heat-sensitive recording material MITSUBISHI PAPER MILLS LTD. (JP) 2005-11-01 US disclosed
US-20030186810-A1 Heat-sensitive recording material MITSUBISHI PAPER MILLS LTD. 2003-10-02 US disclosed