SCHEMBL891165

SCHEMBL891165

CCCCCCOc1cc(N(CC)CC)ccc1C1(c2c(C)n(CC)c3ccccc23)OC(=O)c2cccnc21

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 6/20 0.32
PDE5A O76074 2/20 0.32
PDE4A P27815 2/20 0.32
PDE4B Q07343 2/20 0.32
PDE4C Q08493 2/20 0.32
PDE4D Q08499 2/20 0.32
LMNA P02545 1/20 0.32
HTT P42858 1/20 0.32
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
MEN1 O00255 1/20 0.31
RECQL P46063 1/20 0.31
KMT2A Q03164 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ALDH1A1 P00352 1/20 0.31
PSEN1 P49768 1/20 0.31
PSEN2 P49810 1/20 0.31
APH1B Q8WW43 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29496955 1.00 PLA2G2A (0.32) PLA2G2APDE5APDE4APDE4BPDE4C
SCHEMBL10596820 1.00 PLA2G2A (0.32) PLA2G2APDE5APDE4APDE4BPDE4C
SCHEMBL30009305 1.00 PLA2G2A (0.32) PLA2G2APDE5APDE4APDE4BPDE4C
SCHEMBL10661081 1.00 PLA2G2A (0.32) PLA2G2APDE5APDE4APDE4BPDE4C
SCHEMBL9467342 0.99 LMNA (0.32) PLA2G2APDE5APDE4APDE4BPDE4C
SCHEMBL20987295 0.98 HTT (0.33) LMNAHTTMEN1KMT2ANPSR1
SCHEMBL3178593 0.95 ALDH1A1 (0.33) LMNAHTTMEN1KMT2ANPSR1
SCHEMBL18903772 0.94 LMNA (0.30) LMNAHTTALDH1A1
SCHEMBL8777592 0.93 PLA2G2A (0.33) PLA2G2APDE5APDE4APDE4BPDE4C
SCHEMBL4578856 0.93 CNR2 (0.36) HTTALDH1A1PSEN1PSEN2APH1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 375 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12202994-B2 Thermochromic pigment compositions SOCIETE BIC (FR) 2025-01-21 US claimed
US-12139626-B2 Irreversibly erasable ink composition having a discoloration agent SOCIéTé BIC (FR) 2024-11-12 US claimed
US-12043596-B2 Thermochromic pigment compositions SOCIETE BIC (FR) 2024-07-23 US claimed
CN-115298270-B Method for preparing thermochromic water-based gel ink composition and thermochromic water-based gel ink composition thereof 法国比克公司 2024-03-26 CN claimed
US-11920047-B2 Method for preparing thermochromic water-based gel ink compositions, and thermochromic water-based gel ink compositions thereof SOCIéTé BIC (FR) 2024-03-05 US claimed
EP-3859211-B1 HANDHELD LIGHTER WITH HIGH TEMPERATURE WARNING INDICATOR SOCIéTé BIC (FR) 2024-01-24 EP claimed
US-11814528-B2 Diester of bisphenol fluorene compounds and thermochromic pigment compositions comprising the same SOCIéTé BIC (FR) 2023-11-14 US claimed
US-11787226-B2 Eraser tool containing polyetheramine SOCIETE BIC (FR) 2023-10-17 US claimed
US-20230167325-A1 METHOD FOR PREPARING THERMOCHROMIC WATER-BASED GEL INK COMPOSITIONS, AND THERMOCHROMIC WATER-BASED GEL INK COMPOSITIONS THEREOF SOCIéTé BIC (FR) 2023-06-01 US claimed
US-11655387-B2 Thermochromic pigment compositions SOCIéTé BIC (FR) 2023-05-23 US claimed
US-20180244944-A1 Compound for Use in Colour Change Compositions SOCIETE BIC (FR) 2018-08-30 US claimed
WO-2018150146-A1 NOVEL THERMOCHROMIC PIGMENT COMPOSITION COMPRISING A COMPOUND OF FORMULA (I) AS REACTION MEDIUM SOCIETE BIC (FR) 2018-08-23 WO claimed
EP-3349990-A1 COMPOUND FOR USE IN COLOUR CHANGE COMPOSITIONS Thermographic Measurements Ltd (GB) 2018-07-25 EP claimed
EP-3344468-A1 COMPOUND FOR USE IN COLOUR CHANGE COMPOSITIONS Thermographic Measurements Ltd (GB) 2018-07-11 EP claimed
WO-2017037282-A1 COMPOUND FOR USE IN COLOUR CHANGE COMPOSITIONS THERMOGRAPHIC MEASUREMENTS LTD (GB) 2017-03-09 WO claimed
WO-2017037284-A1 COMPOUND FOR USE IN COLOUR CHANGE COMPOSITIONS THERMOGRAPHIC MEASUREMENTS LTD (GB) 2017-03-09 WO claimed
EP-0587184-B1 Pressure sensitive recording materials NEW OJI PAPER CO LTD (JP) 1997-12-29 EP claimed
US-5478793-A Basic dye-containing layer and color accetpor-containing layer formed on same or different surfaces; basic dye enclosed in synthetic polymer microcapsules, color acceptor is activated clay containing silica KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1995-12-26 US claimed
EP-0587184-A2 Pressure sensitive recording materials NEW OJI PAPER CO., LTD. (JP) 1994-03-16 EP claimed
US-4747875-A Chromogenic azaphthalide compound and a colour-forming recording composition containing the same YAMADA CHEMICAL CO., LTD. (JP) 1988-05-31 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12043596-B2 Thermochromic pigment compositions TYR, MITF, CRY2 PLA2G2A 3352/4885PDE5A 2377/4885PDE4A 2928/4885
US-12202994-B2 Thermochromic pigment compositions TYR, MITF, MC1R PLA2G2A 4055/4885PDE5A 1180/4885PDE4A 2333/4885
US-11814528-B2 Diester of bisphenol fluorene compounds and thermochromic pigment compositions comprising the same TYR, MITF, RB1 PLA2G2A 1805/4885PDE5A 3328/4885PDE4A 2511/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.