SCHEMBL318250

SCHEMBL318250

CC(C)S(=O)(=O)OC(NC(=O)c1c(F)cccc1F)C(=O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ITGB2 P05107 2/20 0.40
ICAM1 P05362 2/20 0.40
ITGAL P20701 2/20 0.40
PSMB1 P20618 1/20 0.38
PSMB5 P28074 1/20 0.38
PSMB2 P49721 1/20 0.38
KAT6A Q92794 3/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
PPIA P62937 1/20 0.36
LMNA P02545 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23355178 0.77 ITGB2 (0.48) ITGB2ICAM1ITGALPSMB1PSMB5
SCHEMBL7135256 0.72 ITGB2 (0.53) ITGB2ICAM1ITGALMEN1KMT2A
SCHEMBL8402596 0.68 SMN1; SMN2 (0.59) ITGB2ICAM1ITGALPSMB1PSMB5
SCHEMBL8402593 0.68 SMN1; SMN2 (0.59) ITGB2ICAM1ITGALPSMB1PSMB5
SCHEMBL23355193 0.68 ITGA4 (0.48) ITGB2ICAM1ITGALLMNASMN1; SMN2
SCHEMBL551858 0.65 ALB (0.47) ITGB2ICAM1ITGALMEN1KMT2A
SCHEMBL163483 0.65 EPHX2 (0.53) ITGB2ICAM1ITGALPSMB1PSMB5
SCHEMBL162523 0.65 EPHX2 (0.53) ITGB2ICAM1ITGALPSMB1PSMB5
SCHEMBL162522 0.65 EPHX2 (0.53) ITGB2ICAM1ITGALPSMB1PSMB5
SCHEMBL28025198 0.64 RAB9A (0.51) MEN1KMT2ANPC1RAB9APPIA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8093241-B2 Acid amide derivatives, process for their production and pesticides containing them ISHIHARA SANGYO KAISHA, LTD. (JP) 2012-01-10 US disclosed
US-20100093707-A1 ACID AMIDE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND PESTICIDES CONTAINING THEM ISHIHARA SANGYO KAISHA, LTD. (JP) 2010-04-15 US disclosed
US-7683096-B2 Acid amide derivatives, process for producing these, and pest control agent containing these ISHIHARA SANGYO KAISHA, LTD. (JP) 2010-03-23 US disclosed
US-20040254237-A1 Acid amide derivatives, process for producing these, and pest agent containing these ISHIHARA SANGYO KAISHA LTD. (JP) 2004-12-16 US disclosed
EP-1428817-A1 ACID AMIDE DERIVATIVES, PROCESS FOR PRODUCING THESE, AND PEST CONTROL AGENT CONTAINING THESE ISHIHARA SANGYO KAISHA, LTD. (JP) 2004-06-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100093707-A1 ACID AMIDE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND PESTICIDES CONTAINING THEM NAA15, SAP18, CYP2C18 ITGB2 4841/4885ICAM1 4766/4885ITGAL 4708/4885
US-20040254237-A1 Acid amide derivatives, process for producing these, and pest agent containing these NAA15, CBR3, CBR1 ITGB2 4711/4885ICAM1 4642/4885ITGAL 4521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.