Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 15/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3182560 | 0.94 | HTR6 (0.51) | HTR6NR3C2 | |
| SCHEMBL3195017 | 0.84 | HTR6 (0.49) | HTR6LMNANR3C2 | |
| SCHEMBL3182634 | 0.84 | HTR6 (0.49) | HTR6LMNANR3C2 | |
| SCHEMBL3187317 | 0.84 | HTR6 (0.48) | HTR6 | |
| SCHEMBL3181438 | 0.83 | HTR6 (0.47) | HTR6 | |
| SCHEMBL3190935 | 0.83 | HTR6 (0.51) | HTR6 | |
| SCHEMBL3178329 | 0.83 | HTR6 (0.51) | HTR6 | |
| SCHEMBL3212533 | 0.82 | LMNA (0.42) | HTR6LMNANR3C2TSHRCYP11B1 | |
| SCHEMBL3199222 | 0.80 | LMNA (0.42) | HTR6LMNANR3C2TSHRCYP11B1 | |
| SCHEMBL3204972 | 0.80 | HTR6 (0.43) | HTR6LMNATSHRCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100022581-A1 | PYRROLIDINE-SUBSTITUTED AZAINDOLE COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-28 | — | — | US | claimed |
| US-20100022581-A1 | PYRROLIDINE-SUBSTITUTED AZAINDOLE COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-28 | — | — | US | disclosed |
| US-20100022581-A1 | PYRROLIDINE-SUBSTITUTED AZAINDOLE COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022581-A1 | PYRROLIDINE-SUBSTITUTED AZAINDOLE COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | HTR6, HTR1A, HTR5A | HTR6 1/4885LMNA 3499/4885NR3C2 332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.