Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.49 |
| ▸ | LTA4H | P09960 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | MLNR | O43193 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304906 | 0.88 | LTA4H (0.60) | LTA4HCNR1MLNRNR1I2ESR1 | |
| SCHEMBL18302044 | 0.88 | LTA4H (0.60) | LTA4HCNR1MLNRNR1I2ESR1 | |
| SCHEMBL539283 | 0.87 | PLA2G2A (0.44) | PLA2G2ALTA4HCNR1MAPK1SMN1; SMN2 | |
| SCHEMBL15470861 | 0.79 | MEN1 (0.39) | PLA2G2ACNR1ESR1DRD2DRD3 | |
| SCHEMBL9016884 | 0.76 | PLA2G2A (0.68) | PLA2G2ALTA4HCNR1MLNRNR1I2 | |
| SCHEMBL18886699 | 0.76 | PLA2G2A (0.68) | PLA2G2ALTA4HCNR1MLNRNR1I2 | |
| SCHEMBL17247317 | 0.74 | LTA4H (0.64) | LTA4HCNR1MLNRNR1I2ESR1 | |
| SCHEMBL17241274 | 0.74 | LTA4H (0.64) | LTA4HCNR1MLNRNR1I2ESR1 | |
| SCHEMBL17241411 | 0.74 | LTA4H (0.64) | LTA4HCNR1MLNRNR1I2ESR1 | |
| SCHEMBL25205847 | 0.74 | LTA4H (0.81) | LTA4HCNR1MLNRNR1I2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293948-B2 | Reagent for organic synthesis and method of organic synthesis reaction with the reagent | JITSUBO CO., LTD. (JP) | 2012-10-23 | — | — | US | disclosed |
| US-20120108788-A1 | REAGENT FOR ORGANIC SYNTHESIS AND METHOD OF ORGANIC SYNTHESIS REACTION WITH THE REAGENT | JITSUBO CO., LTD. (JP) | 2012-05-03 | — | — | US | disclosed |
| US-8093435-B2 | Reagent for organic synthesis and method of organic synthesis reaction with the reagent | JITSUBO CO., LTD. (JP) | 2012-01-10 | — | — | US | disclosed |
| US-20090299103-A1 | Reagent for Organic Synthesis and Method of Organic Synthesis Reaction with the Reagent | NATIONAL UNIVERSITY CORPORATION, TOKYO UNIVERSITY (JP) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090299103-A1 | Reagent for Organic Synthesis and Method of Organic Synthesis Reaction with the Reagent | COASY, OSTC, OGA | PLA2G2A 4670/4885LTA4H 399/4885CNR1 3759/4885 |
| US-20120108788-A1 | REAGENT FOR ORGANIC SYNTHESIS AND METHOD OF ORGANIC SYNTHESIS REACTION WITH THE REAGENT | COASY, OSTC, OGA | PLA2G2A 4670/4885LTA4H 399/4885CNR1 3759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.