Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.44 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 4/20 | 0.38 |
| ▸ | CNR2 | P34972 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15470861 | 0.92 | MEN1 (0.39) | PLA2G2ANR5A1TSHRTHRBCNR1 | |
| SCHEMBL318324 | 0.87 | PLA2G2A (0.49) | PLA2G2ANR5A1TSHRBLMCNR1 | |
| SCHEMBL13165994 | 0.85 | PLA2G2A (0.44) | PLA2G2ANR5A1TSHRBLMTHRB | |
| SCHEMBL538922 | 0.83 | ESR1 (0.40) | THRBKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL15470859 | 0.81 | ESR1 (0.44) | THRBCNR1CNR2KMT2ARAB9A | |
| SCHEMBL5599322 | 0.77 | NR5A1 (0.66) | NR5A1TSHRTP53LTA4HNPC1 | |
| SCHEMBL6122097 | 0.77 | NR5A1 (0.66) | NR5A1TSHRTP53LTA4HNPC1 | |
| SCHEMBL11662072 | 0.77 | NR5A1 (0.66) | NR5A1TSHRTP53LTA4HNPC1 | |
| SCHEMBL9304906 | 0.77 | LTA4H (0.60) | NR5A1TSHRCNR1TP53LTA4H | |
| SCHEMBL18302044 | 0.77 | LTA4H (0.60) | NR5A1TSHRCNR1TP53LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9029504-B2 | Fluorene compound | AJINOMOTO CO., INC. (JP) | 2015-05-12 | — | — | US | disclosed |
| US-20140046022-A1 | FLUORENE COMPOUND | AJINOMOTO CO., INC. (JP) | 2014-02-13 | — | — | US | disclosed |
| US-8569453-B2 | Fluorene compound | AJINOMOTO CO., INC. (JP) | 2013-10-29 | — | — | US | disclosed |
| US-8569453-B2 | Fluorene compound | AJINOMOTO CO., INC. (JP) | 2013-10-29 | — | — | US | disclosed |
| EP-2415744-A1 | FLUORENE COMPOUND | Ajinomoto Co., Inc. (JP) | 2012-02-08 | — | — | EP | disclosed |
| US-20100240867-A1 | FLUORENE COMPOUND | AJINOMOTO CO. INC. (JP) | 2010-09-23 | — | — | US | disclosed |
| US-20100240867-A1 | FLUORENE COMPOUND | AJINOMOTO CO. INC. (JP) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140046022-A1 | FLUORENE COMPOUND | NPPA, FURIN, SFPQ | PLA2G2A 4293/4885NR5A1 3555/4885TSHR 1689/4885 |
| US-20100240867-A1 | FLUORENE COMPOUND | NPPA, FURIN, SFPQ | PLA2G2A 4293/4885NR5A1 3555/4885TSHR 1689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.