Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.38 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44725 | 0.89 | ALDH1A1 (0.50) | ALDH1A1PKMEHMT2EHMT1APOBEC3G | |
| SCHEMBL28279888 | 0.88 | ALDH1A1 (0.40) | ALDH1A1PKMEHMT2EHMT1APOBEC3G | |
| SCHEMBL1752117 | 0.80 | ALDH1A1 (0.48) | ALDH1A1PKMEHMT2EHMT1APOBEC3G | |
| Hydrogen Sulfide SCHEMBL20305480 | 0.79 | ALDH1A1 (0.47) | ALDH1A1PKMEHMT2EHMT1APOBEC3G | |
| SCHEMBL3490799 | 0.78 | ALDH1A1 (0.46) | ALDH1A1PKMEHMT2EHMT1APOBEC3G | |
| SCHEMBL616908 | 0.77 | ALDH1A1 (0.54) | ALDH1A1PKMKMT2AMEN1MAPT | |
| SCHEMBL28630260 | 0.77 | HDAC1 (0.41) | ALDH1A1PKMNPC1RAB9ALMNA | |
| SCHEMBL10340280 | 0.77 | HDAC1 (0.47) | ALDH1A1PKMKMT2AMAPTHDAC4 | |
| SCHEMBL29141153 | 0.74 | ELANE (0.32) | ALDH1A1PKM | |
| SCHEMBL9281376 | 0.74 | ALDH1A1 (0.36) | ALDH1A1PKMEHMT2EHMT1APOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200190199-A1 | ANTIBODY-DRUG CONJUGATES AND USES THEREOF | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 2020-06-18 | — | — | US | claimed |
| US-20050276863-A1 | Methods for treatment of aneurysmal tissue | MEDTRONIC VASCULAR, INC. (US) | 2005-12-15 | — | — | US | claimed |
| EP-1602925-A2 | Methods for treatment of aneurysmal tissue | Medtronic Vascular, Inc. (US) | 2005-12-07 | — | — | EP | claimed |
| US-20230414527-A1 | FIBRIN PARTICLES AND METHODS OF MAKING THE SAME | NORTH CAROLINA STATE UNIVERSITY | 2023-12-28 | — | — | US | disclosed |
| US-11786477-B2 | Fibrin particles and methods of making the same | NORTH CAROLINA STATE UNIVERSITY (US) | 2023-10-17 | — | — | US | disclosed |
| US-11384150-B2 | Antibody-drug conjugates and uses thereof | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 2022-07-12 | — | — | US | disclosed |
| CN-113518923-A | Method for the production of lipidated protein structures | 默克专利股份公司 | 2021-10-19 | — | — | CN | disclosed |
| US-20210169813-A1 | FIBRIN PARTICLES AND METHODS OF MAKING THE SAME | NORTH CAROLINA STATE UNIVERSITY | 2021-06-10 | — | — | US | disclosed |
| US-20200190199-A1 | ANTIBODY-DRUG CONJUGATES AND USES THEREOF | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 2020-06-18 | — | — | US | disclosed |
| WO-2018093864-A1 | NANOPARTICLE CONJUGATES AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-05-24 | — | — | WO | disclosed |
| US-20180133343-A1 | NANOPARTICLE CONJUGATES AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-05-17 | — | — | US | disclosed |
| EP-1602925-B1 | System for treatment of aneurysmal tissue | MEDTRONIC VASCULAR INC (US) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007122259-A1 | FUNCTIONALIZATION OF GOLD NANOPARTICLES WITH ORIENTED PROTEINS. APPLICATION TO THE HIGH-DENSITY LABELLING OF CELL MEMBRANES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2007-11-01 | — | — | WO | disclosed |
| US-20060199207-A1 | Self-assembly of molecules using combinatorial hybridization | APPLIED BIOSYSTEMS, LLC | 2006-09-07 | — | — | US | disclosed |
| US-20060057573-A1 | Methods and reagents for detecting target binding by nucleic acid ligands | SOMALOGIC, INC (US) | 2006-03-16 | — | — | US | disclosed |
| US-20050282239-A1 | Cell-permeable enzyme activation reporter that can be loaded in a high throughput and gentle manner | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-12-22 | — | — | US | disclosed |
| US-20050276863-A1 | Methods for treatment of aneurysmal tissue | MEDTRONIC VASCULAR, INC. (US) | 2005-12-15 | — | — | US | disclosed |
| EP-1602925-A2 | Methods for treatment of aneurysmal tissue | Medtronic Vascular, Inc. (US) | 2005-12-07 | — | — | EP | disclosed |
| EP-1481090-A1 | METHODS AND REAGENTS FOR DETECTING TARGET BINDING BY NUCLEIC ACID LIGANDS | SomaLogic, Inc. (US) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003070984-A1 | METHODS AND REAGENTS FOR DETECTING TARGET BINDING BY NUCLEIC ACID LIGANDS | SOMALOGIC, INC. (US) | 2003-08-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180133343-A1 | NANOPARTICLE CONJUGATES AND USES THEREOF | CD47, EPCAM, FCGR2A | ALDH1A1 956/4885PKM 4356/4885EHMT2 774/4885 |
| US-11384150-B2 | Antibody-drug conjugates and uses thereof | EGFR, ERBB2, ERBB3 | ALDH1A1 3084/4885PKM 3444/4885EHMT2 3249/4885 |
| US-20200190199-A1 | ANTIBODY-DRUG CONJUGATES AND USES THEREOF | EGFR, ERBB2, ERBB3 | ALDH1A1 3084/4885PKM 3444/4885EHMT2 3249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.