SCHEMBL3184384

SCHEMBL3184384

O=C(O)c1cccc(Oc2cc(-c3ccccc3)c(C(F)(F)F)c(C(F)(F)F)c2Oc2cccc(C(=O)O)c2C(=O)O)c1C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.38
HNF4A P41235 1/20 0.37
LTB4R Q15722 4/20 0.35
LTB4R2 Q9NPC1 4/20 0.35
PTPN1 P18031 1/20 0.35
HTT P42858 1/20 0.35
FABP4 P15090 1/20 0.34
PTGDR2 Q9Y5Y4 1/20 0.34
S1PR1 P21453 1/20 0.34
SYK P43405 1/20 0.34
CCR1 P32246 1/20 0.34
CCR2 P41597 1/20 0.34
RORC P51449 1/20 0.33
RORB Q92753 1/20 0.33
ANO1 Q5XXA6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3193266 0.88 BACE1 (0.38) BACE1HNF4APTPN1FABP4PTGDR2
SCHEMBL3193261 0.84 BACE1 (0.38) BACE1FABP4PTGDR2S1PR1RORC
SCHEMBL29962764 0.84 MAPK1 (0.41) HTTCCR1CCR2
SCHEMBL29406692 0.82 MAPK1 (0.40) HTTCCR1CCR2
SCHEMBL3194765 0.82 MAPK1 (0.40) HTTCCR1CCR2
SCHEMBL6405077 0.80 HTT (0.36) HNF4AHTTFABP4CCR1CCR2
SCHEMBL28773737 0.80 FABP4 (0.44) HNF4AFABP4S1PR1SYKRORC
SCHEMBL10699812 0.79 HNF4A (0.49) HNF4ALTB4RLTB4R2HTTFABP4
SCHEMBL3193357 0.78 TAS2R14 (0.38) HTTFABP4CCR1CCR2
SCHEMBL29406931 0.78 TAS2R14 (0.38) HTTFABP4CCR1CCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0400635-B1 Liquid crystal device CANON KK (JP) 1995-09-27 EP claimed
US-5192596-A Polyimide CANON KABUSHIKI KAISHA (JP) 1993-03-09 US claimed
EP-0400635-A2 Liquid crystal device CANON KABUSHIKI KAISHA (JP) 1990-12-05 EP claimed
EP-4446360-A1 POLYIMIDE FOR SPACECRAFT, POLYIMIDE FILM FOR SPACECRAFT, AND SPACECRAFT MEMBER INCLUDING SAME NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2024-10-16 EP disclosed
WO-2024071066-A1 METAL-CLAD LAMINATED PLATE 日鉄ケミカル&マテリアル株式会社 2024-04-04 WO disclosed
WO-2023189319-A1 AMINO COMPOUND, POLYAMIDE ACID AND POLYIMIDE USING SAID AMINO COMPOUND, AND METHOD FOR PRODUCING SAME 日鉄ケミカル&マテリアル株式会社 2023-10-05 WO disclosed
WO-2023106369-A1 POLYIMIDE FOR SPACECRAFT, POLYIMIDE FILM FOR SPACECRAFT, AND SPACECRAFT MEMBER INCLUDING SAME 日鉄ケミカル&マテリアル株式会社 2023-06-15 WO disclosed
US-20210340325-A1 POLYIMIDE PRECURSOR, POLYIMIDE PRODUCED FROM SAME, AND FLEXIBLE DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2021-11-04 US disclosed
US-10696845-B2 Energy-sensitive resin composition TOKYO OHKA KOGYO CO., LTD. (JP) 2020-06-30 US disclosed
EP-3275940-B1 ENERGY-SENSITIVE RESIN COMPOSITION TOKYO OHKA KOGYO CO LTD (JP) 2019-12-18 EP disclosed
US-20190225804-A1 ENERGY-SENSITIVE RESIN COMPOSITION TOKYO OHKA KOGYO CO., LTD. (JP) 2019-07-25 US disclosed
EP-0616234-A2 Polyimide optical waveguide and method of manufacturing the same NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1994-09-21 EP disclosed
US-5316805-A Liquid crystal device CANON KABUSHIKI KAISHA (JP) 1994-05-31 US disclosed
EP-0219336-B1 LIQUID CRYSTAL ORIENTATION CONTROLLING FILM AND LIQUID CRYSTAL DEVICE USING THE SAME Hitachi Chemical Co., Ltd. (JP) 1993-07-21 EP disclosed
US-5192596-A Polyimide CANON KABUSHIKI KAISHA (JP) 1993-03-09 US disclosed
US-5108201-A From 3,3'-diamino-2,2'-bis(trifluoromethyl)biphenyl monomer NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1992-04-28 US disclosed
EP-0454590-A2 Polyimide optical waveguide NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1991-10-30 EP disclosed
EP-0400635-A2 Liquid crystal device CANON KABUSHIKI KAISHA (JP) 1990-12-05 EP disclosed
US-4735492-A POLYIMIDE-ISOIDOLOQUINAZOLINEDIONE HITACHI CHEMICAL COMPANY, LTD. (JP) 1988-04-05 US disclosed
EP-0219336-A2 Liquid crystal orientation controlling film and liquid crystal device using the same Hitachi Chemical Co., Ltd. (JP) 1987-04-22 EP disclosed