SCHEMBL6405077

SCHEMBL6405077

O=C(O)c1cccc(Oc2ccccc2-c2c(Oc3cccc(C(=O)O)c3C(=O)O)c(C(F)(F)F)c(C(F)(F)F)c(C(F)(F)F)c2C(F)(F)F)c1C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.36
HNF4A P41235 1/20 0.35
CCR1 P32246 2/20 0.34
CCR2 P41597 2/20 0.34
ALDH1A1 P00352 4/20 0.34
LMNA P02545 2/20 0.34
MYC P01106 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MAPT P10636 1/20 0.34
KDM4E B2RXH2 4/20 0.33
HSD17B10 Q99714 4/20 0.33
HPGD P15428 3/20 0.33
FABP4 P15090 1/20 0.33
FOLH1 Q04609 2/20 0.33
MAPK1 P28482 1/20 0.33
PTGER1 P34995 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
ESR1 P03372 1/20 0.32
ITGB3 P05106 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29406692 0.86 MAPK1 (0.40) HTTCCR1CCR2ALDH1A1MAPT
SCHEMBL3194765 0.86 MAPK1 (0.40) HTTCCR1CCR2ALDH1A1MAPT
SCHEMBL29962764 0.85 MAPK1 (0.41) HTTCCR1CCR2ALDH1A1MAPT
SCHEMBL3184384 0.80 BACE1 (0.38) HTTHNF4ACCR1CCR2FABP4
SCHEMBL10699806 0.79 HTT (0.50) HTTHNF4AALDH1A1LMNAMYC
SCHEMBL3744942 0.77 TAS2R14 (0.40) ALDH1A1LMNAHPGDFABP4MAPK1
SCHEMBL6405070 0.77 TAS2R14 (0.35) HTTCCR1CCR2ALDH1A1KDM4E
SCHEMBL3193357 0.77 TAS2R14 (0.38) HTTCCR1CCR2FABP4MAPK1
SCHEMBL29406931 0.77 TAS2R14 (0.38) HTTCCR1CCR2FABP4MAPK1
SCHEMBL3755844 0.76 HTT (0.39) HTTCCR1CCR2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0400635-B1 Liquid crystal device CANON KK (JP) 1995-09-27 EP claimed
US-5192596-A Polyimide CANON KABUSHIKI KAISHA (JP) 1993-03-09 US claimed
EP-0400635-A2 Liquid crystal device CANON KABUSHIKI KAISHA (JP) 1990-12-05 EP claimed
US-9688815-B2 Method for producing polyimide precursor and method for producing polyimide RICOH COMPANY, LTD. (JP) 2017-06-27 US disclosed
US-20160122474-A1 METHOD FOR PRODUCING POLYIMIDE PRECURSOR AND METHOD FOR PRODUCING POLYIMIDE RICHO COMPANY, LTD. (JP) 2016-05-05 US disclosed
EP-3004211-A1 METHOD FOR PRODUCING POLYIMIDE PRECURSOR AND METHOD FOR PRODUCING POLYIMIDE Ricoh Company, Ltd. (JP) 2016-04-13 EP disclosed
WO-2014192665-A1 METHOD FOR PRODUCING POLYIMIDE PRECURSOR AND METHOD FOR PRODUCING POLYIMIDE RICOH COMPANY, LTD. (JP) 2014-12-04 WO disclosed
US-20120177425-A1 GLOSSY SURFACE FORMING APPARATUS AND GLOSSY SURFACE FORMING METHOD KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2012-07-12 US disclosed
US-20050136245-A1 Intermediate transfer medium, film forming liquid for the intermediate transfer medium and image forming apparatus using intermediate transfer medium RICOH COMPANY LIMITED (JP) 2005-06-23 US disclosed
US-5571579-A FORMING A POLYIMIDE FILM AND RUBBING THE SURFACE OF THE FILM HITACHI CHEMICAL COMPANY, LTD (JP) 1996-11-05 US disclosed
EP-0400635-B1 Liquid crystal device CANON KK (JP) 1995-09-27 EP disclosed
EP-0397153-B1 Chiral smectic liquid crystal device CANON KK (JP) 1995-08-02 EP disclosed
US-5426525-A Ferroelectric smectic liquid crystal device CANON KABUSHIKI KAISHA (JP) 1995-06-20 US disclosed
US-5316805-A Liquid crystal device CANON KABUSHIKI KAISHA (JP) 1994-05-31 US disclosed
US-5192596-A Polyimide CANON KABUSHIKI KAISHA (JP) 1993-03-09 US disclosed
EP-0400635-A2 Liquid crystal device CANON KABUSHIKI KAISHA (JP) 1990-12-05 EP disclosed
EP-0219336-A2 Liquid crystal orientation controlling film and liquid crystal device using the same Hitachi Chemical Co., Ltd. (JP) 1987-04-22 EP disclosed