2-Naphthaldehyde

2-Naphthaldehyde

SCHEMBL3184404

C(=NC(N=Cc1ccccc1)c1ccccc1)c1ccccc1.O=Cc1ccc2ccccc2c1

nearest known ligand 0.45

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 1/20 0.45
ALDH1A1 P00352 5/20 0.42
KDM4E B2RXH2 3/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
RAB9A P51151 1/20 0.38
GRIN2D O15399 2/20 0.38
GRIN3B O60391 2/20 0.38
GRIN1 Q05586 2/20 0.38
GRIN2A Q12879 2/20 0.38
GRIN2B Q13224 2/20 0.38
GRIN2C Q14957 2/20 0.38
GRIN3A Q8TCU5 2/20 0.38
LMNA P02545 3/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
GAA P10253 2/20 0.38
MAPT P10636 2/20 0.38
THRB P10828 1/20 0.38
ALOX12 P18054 1/20 0.38
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzaldehyde SCHEMBL3185067 0.84 ALDH1A1 (0.54) ALDH1A1L3MBTL1GRIN2DGRIN3BGRIN1
SCHEMBL3196513 0.79 ALDH1A1 (0.34) ALDH1A1L3MBTL1LMNAMAPTCYP2A6
SCHEMBL151524 0.79 LMNA (0.50) ALDH1A1L3MBTL1GRIN2DGRIN3BGRIN1
SCHEMBL14163512 0.79 LMNA (0.50) ALDH1A1L3MBTL1GRIN2DGRIN3BGRIN1
2-Naphthaldehyde SCHEMBL28866061 0.79 RELA (0.61) RELAALDH1A1KDM4EL3MBTL1RAB9A
SCHEMBL3186046 0.78 RRM1 (0.38) ALDH1A1KDM4EL3MBTL1RAB9ALMNA
2-Naphthaldehyde SCHEMBL51340 0.77 RELA (0.58) RELAALDH1A1KDM4EL3MBTL1RAB9A
2-Naphthaldehyde SCHEMBL30229844 0.77 RELA (0.58) RELAALDH1A1KDM4EL3MBTL1RAB9A
2-Naphthaldehyde SCHEMBL27347080 0.77 RELA (0.58) RELAALDH1A1KDM4EL3MBTL1RAB9A
2-Naphthaldehyde SCHEMBL28110154 0.77 RELA (0.58) RELAALDH1A1KDM4EL3MBTL1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7671138-B2 Polymers functionized with hydrobenzamides BRIDGESTONE CORPORATION (JP) 2010-03-02 US claimed
US-20070276122-A1 Polymers functionalized with hydrobenzamides BRIDGESTONE CORPORATION 2007-11-29 US claimed
US-20070276098-A1 Polymers functionalized with hydrobenzamide BRIDGESTONE CORPORATION 2007-11-29 US claimed
US-7671138-B2 Polymers functionized with hydrobenzamides BRIDGESTONE CORPORATION (JP) 2010-03-02 US disclosed
US-20070276098-A1 Polymers functionalized with hydrobenzamide BRIDGESTONE CORPORATION 2007-11-29 US disclosed
US-20070276122-A1 Polymers functionalized with hydrobenzamides BRIDGESTONE CORPORATION 2007-11-29 US disclosed