Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.81 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.57 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.57 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.57 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 4/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | HRH1 | P35367 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Heptane SCHEMBL7969065 | 0.97 | CA2 (0.77) | CA2MAPK1SLC1A2SLC1A1GRIK1 | |
| Hexane SCHEMBL9784833 | 0.95 | CA2 (0.74) | CA2MAPK1SLC1A2SLC1A1GRIK1 | |
| SCHEMBL29946 | 0.93 | CA2 (0.86) | CA2MAPK1SLC1A2SLC1A1GRIK1 | |
| 2-Ethylhexanoic Acid SCHEMBL8391670 | 0.93 | CA2 (0.95) | CA2MAPK1SLC1A2SLC1A1GRIK1 | |
| SCHEMBL8606737 | 0.93 | CA2 (0.86) | CA2MAPK1SLC1A2SLC1A1GRIK1 | |
| SCHEMBL23829870 | 0.93 | CA2 (0.86) | CA2MAPK1SLC1A2SLC1A1GRIK1 | |
| SCHEMBL249553 | 0.91 | CA2 (0.83) | CA2MAPK1SLC1A2SLC1A1GRIK1 | |
| Hexane SCHEMBL4788148 | 0.91 | CA2 (0.83) | CA2MAPK1SLC1A2SLC1A1GRIK1 | |
| SCHEMBL3003696 | 0.91 | CA2 (0.83) | CA2MAPK1SLC1A2SLC1A1GRIK1 | |
| SCHEMBL2492860 | 0.91 | CA2 (0.83) | CA2MAPK1SLC1A2SLC1A1GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102124010-B | Isosorbide nitrates having vasodilating activity | LACER SA | 2013-12-18 | — | — | CN | disclosed |
| EP-2324033-B1 | ISOSORBIDE NITRATES HAVING VASODILATING ACTIVITY | LACER SA (ES) | 2012-08-22 | — | — | EP | disclosed |
| US-20120189616-A1 | ISOSORBIDE NITRATES | LACER, S.A. (ES) | 2012-07-26 | — | — | US | disclosed |
| US-8211939-B2 | Isosorbide nitrates | LACER, S.A. (ES) | 2012-07-03 | — | — | US | disclosed |
| CN-102124010-A | Isosorbide nitrates having vasodilating activity | LACER SA | 2011-07-13 | — | — | CN | disclosed |
| EP-2149576-A1 | Isosorbide Nitrates having vasodilating activity | LACER, S.A. (ES) | 2010-02-03 | — | — | EP | disclosed |
| US-20100022638-A1 | ISOSORBIDE NITRATES | LACER, S. A. (ES) | 2010-01-28 | — | — | US | disclosed |
| US-6812331-B2 | BACTERICIDES | AVENTIS PHARMA S.A. (FR) | 2004-11-02 | — | — | US | disclosed |
| US-6350733-B1 | 4-HYDROXYBENZOPYRAN-2-ONE DERIVATIVES; BACTERICIDES FOR STAPHYLOCOCCUS INFECTIONS; SKIN DISORDERS | AVENTIS PHARMA S.A. (FR) | 2002-02-26 | — | — | US | disclosed |
| US-20020010322-A1 | New aromatic derivatives substituted by a ribose, their preparation process and their use as medicaments | AVENTIS PHARMA S.A. | 2002-01-24 | — | — | US | disclosed |
| US-5153200-A | Insecticides, microbiocides | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| WO-1991019002-A1 | A PROCESS FOR CHIRAL ENRICHMENT OF ASYMMETRIC PRIMARY AMINES | CARLBIOTECH LTD. A/S (DK) | 1991-12-12 | — | — | WO | disclosed |
| US-4997941-A | Insecticides for plant protection, also used as fungicides | CIBA-GEIGY CORPORATION (US) | 1991-03-05 | — | — | US | disclosed |
| US-4931560-A | FUNGICIDES | CIBA-GEIGY CORPORATION (US) | 1990-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120189616-A1 | ISOSORBIDE NITRATES | NOS3, NOX3, NOS2 | CA2 2433/4885MAPK1 2333/4885SLC1A2 3608/4885 |
| US-20020010322-A1 | New aromatic derivatives substituted by a ribose, their preparation process and their use as medicaments | RPIA, CD38, PARP1 | CA2 3436/4885MAPK1 3414/4885SLC1A2 4556/4885 |
| US-20100022638-A1 | ISOSORBIDE NITRATES | NOS3, NOX3, NOS2 | CA2 2433/4885MAPK1 2333/4885SLC1A2 3608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.