Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | NCF1 | P14598 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GPR3 | P46089 | 1/20 | 0.47 |
| ▸ | GALR3 | O60755 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30824509 | 1.00 | MAPT (0.67) | MAPTCYP1A2LMNANCF1L3MBTL1 | |
| SCHEMBL3642682 | 0.80 | L3MBTL1 (0.50) | MAPTCYP1A2LMNANCF1L3MBTL1 | |
| SCHEMBL397020 | 0.78 | MAOA (0.54) | MAPTCYP1A2HTTMAOAMAOB | |
| SCHEMBL29420516 | 0.78 | MAOA (0.54) | MAPTCYP1A2HTTMAOAMAOB | |
| SCHEMBL29502790 | 0.78 | CYP1A2 (1.00) | MAPTCYP1A2LMNANCF1L3MBTL1 | |
| SCHEMBL89010 | 0.78 | CYP1A2 (1.00) | MAPTCYP1A2LMNANCF1L3MBTL1 | |
| SCHEMBL4745343 | 0.78 | POLB (0.72) | MAPTLMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL10824124 | 0.78 | LMNA (0.72) | MAPTCYP1A2LMNANCF1L3MBTL1 | |
| SCHEMBL30572382 | 0.78 | LMNA (1.00) | MAPTCYP1A2LMNAL3MBTL1HTT | |
| SCHEMBL4768081 | 0.78 | LMNA (1.00) | MAPTCYP1A2LMNAL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 509 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118791429-A | Preparation method of 4-chloroquinaldine | 湖北省宏源药业科技股份有限公司 | 2024-10-18 | — | — | CN | claimed |
| CN-118561900-A | Quinoline axial substituted silicon phthalocyanine and preparation method and application thereof | 福建师范大学 | 2024-08-30 | — | — | CN | claimed |
| CN-118164980-A | Thiazole orange derivative, preparation method and application thereof | 国科温州研究院(温州生物材料与工程研究所) | 2024-06-11 | — | — | CN | claimed |
| CN-118047720-A | Preparation method of dequalinium chloride | 美享生物科技(海南)有限公司 | 2024-05-17 | — | — | CN | claimed |
| CN-116143693-A | 2-methylquinoline derivative with anti-tumor activity and synthesis method and application thereof | 中国药科大学 | 2023-05-23 | — | — | CN | claimed |
| CN-111825610-B | 2-methylquinoline derivative with anti-tumor activity and synthesis method and application thereof | 中国药科大学 | 2023-03-31 | — | — | CN | claimed |
| CN-110526910-B | Thiazole orange benzyl quaternary ammonium salt derivative and preparation method and application thereof | 广东工业大学 | 2023-01-20 | — | — | CN | claimed |
| CN-112174885-B | P-dimethylamino styrene quinoline derivative, synthetic method thereof and application thereof in nucleic acid fluorescent probe | 广东工业大学 | 2022-10-04 | — | — | CN | claimed |
| CN-113773302-A | Quinoline compound and preparation method and application thereof | 广东工业大学 | 2021-12-10 | — | — | CN | claimed |
| CN-111018777-B | Preparation method of dequalinium chloride | 武汉智顿科技发展有限公司 | 2021-02-12 | — | — | CN | claimed |
| US-20100216988-A1 | Regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles | SANOFI-AVENTIS (FR) | 2010-08-26 | — | — | US | claimed |
| EP-2173721-A1 | A REGIOSELECTIVE COPPER CATALYZED SYNTHESIS OF BENZIMIDAZOLES AND AZABENZIMIDAZOLES | Sanofi-Aventis (FR) | 2010-04-14 | — | — | EP | claimed |
| EP-2173747-A1 | A REGIOSELECTIVE METAL CATALYZED SYNTHESIS OF ANNELATED BENZIMIDAZOLES AND AZABENZIMIDAZOLES | Sanofi-Aventis (FR) | 2010-04-14 | — | — | EP | claimed |
| CN-101687865-A | A regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles | SANOFI AVENTIS | 2010-03-31 | — | — | CN | claimed |
| CN-101687815-A | Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles | SANOFI AVENTIS | 2010-03-31 | — | — | CN | claimed |
| WO-2009000413-A1 | A REGIOSELECTIVE COPPER CATALYZED SYNTHESIS OF BENZIMIDAZOLES AND AZABENZIMIDAZOLES | SANOFI-AVENTIS (FR) | 2008-12-31 | — | — | WO | claimed |
| WO-2009000412-A1 | A REGIOSELECTIVE METAL CATALYZED SYNTHESIS OF ANNELATED BENZIMIDAZOLES AND AZABENZIMIDAZOLES | SANOFI AVENTIS (FR) | 2008-12-31 | — | — | WO | claimed |
| US-5939568-A | Accelerated catalysis of olefinic epoxidations | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-08-17 | — | — | US | claimed |
| WO-1998033786-A9 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | — | 1998-12-30 | — | — | WO | claimed |
| WO-1998033786-A1 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-08-06 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216988-A1 | Regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles | AZI2, NIT2, NISCH | MAPT 4209/4885CYP1A2 92/4885LMNA 4786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.